Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.43 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855547 | 0.93 | TAAR1 (0.54) | TAAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL2850598 | 0.93 | KDM4E (0.47) | ALDH1A1KDM4EMAPTTP53FAAH | |
| SCHEMBL2851231 | 0.91 | MAPT (0.46) | L3MBTL1ALDH1A1KDM4EMAPTFAAH | |
| SCHEMBL2859861 | 0.89 | TAAR1 (0.51) | TAAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL2860669 | 0.88 | TAAR1 (0.46) | TAAR1LMNAALDH1A1CNR1KDM4E | |
| SCHEMBL2853388 | 0.87 | CCR1 (0.48) | ALDH1A1KDM4ECNR2MAPTTP53 | |
| SCHEMBL2852505 | 0.87 | ABCB1 (0.48) | TAAR1LMNAALDH1A1CNR1MAPT | |
| SCHEMBL2854509 | 0.86 | KDM4E (0.50) | TAAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL2852221 | 0.85 | ALDH1A1 (0.46) | TAAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL2860458 | 0.85 | TP53 (0.46) | TAAR1LMNAL3MBTL1CNR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |