Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850598 | 0.94 | KDM4E (0.47) | MAPTKDM4EALDH1A1FAAHPOLB | |
| SCHEMBL2854346 | 0.93 | MAPT (0.52) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL2856944 | 0.91 | TAAR1 (0.46) | MAPTKMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL2856562 | 0.89 | MAPT (0.48) | MAPTKMT2ANPC1RAB9AKDM4E | |
| SCHEMBL2863154 | 0.88 | MAPT (0.45) | MAPTKDM4EALDH1A1TSHRL3MBTL1 | |
| SCHEMBL2854804 | 0.87 | MAPK1 (0.48) | MAPTRAB9AKDM4EALDH1A1P2RX7 | |
| SCHEMBL2854509 | 0.87 | KDM4E (0.50) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL2860253 | 0.85 | PLAAT3 (0.47) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL2862820 | 0.85 | P2RX7 (0.45) | MAPTKDM4ETSHRL3MBTL1P2RX7 | |
| SCHEMBL2855547 | 0.84 | TAAR1 (0.54) | MAPTNPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |