Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856356 | 0.96 | ALDH1A1 (0.47) | CCR1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL2861243 | 0.92 | KDM4E (0.52) | CCR1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL2856294 | 0.92 | CCR1 (0.49) | CCR1KDM4EALDH1A1ABCB1 | |
| SCHEMBL2854322 | 0.91 | ABCB1 (0.45) | CCR1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2850425 | 0.91 | P2RX7 (0.49) | CCR1RAB9AMAPTPOLBP2RX7 | |
| SCHEMBL2853334 | 0.91 | CCR1 (0.47) | CCR1ALDH1A1MAPTHPGDP2RX7 | |
| SCHEMBL2854804 | 0.91 | MAPK1 (0.48) | CCR1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL2860715 | 0.91 | ALDH1A1 (0.46) | CCR1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL2854852 | 0.90 | ABCB1 (0.49) | CCR1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2855547 | 0.90 | TAAR1 (0.54) | CCR1NPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |