SCHEMBL28569774

SCHEMBL28569774

O=S(=O)(CC(F)(F)F)NCCO

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ATR Q13535 1/20 0.32
ALDH1A1 P00352 3/20 0.32
CYP2C19 P33261 1/20 0.32
GAA P10253 1/20 0.31
PKM P14618 1/20 0.31
CETP P11597 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diethanolamine SCHEMBL21629318 0.78 CA3 (0.31)
SCHEMBL15226205 0.73 CETP (0.38) CETP
SCHEMBL1810926 0.72 RELA (0.34)
SCHEMBL13104023 0.72 ALDH1A1 (0.41) ALDH1A1GAAPKM
SCHEMBL1661515 0.71 EPHX1 (0.33) ALDH1A1CETP
SCHEMBL606519 0.71 EPHX1 (0.52) ALDH1A1CYP2C19GAAPKM
Monoethanolamine SCHEMBL21629309 0.71 ALDH1A1 (0.35) ALDH1A1
SCHEMBL16190192 0.71
SCHEMBL27398548 0.71 ATR (0.40) ATRALDH1A1GAAPKM
SCHEMBL4323234 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112979509-B Trifluoromethanesulfonyl alkynamide compound and preparation method and application thereof 江西师范大学 2022-04-22 CN disclosed
CN-112979509-A Trifluoromethanesulfonyl alkynamide compound and preparation method and application thereof 江西师范大学 2021-06-18 CN disclosed