SCHEMBL606519

SCHEMBL606519

O=S(=O)(NCCO)C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.52
CA2 P00918 5/20 0.46
CA1 P00915 4/20 0.46
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
CA7 P43166 1/20 0.35
CA13 Q8N1Q1 1/20 0.35
ALDH1A1 P00352 3/20 0.33
CYP2C19 P33261 2/20 0.33
IDO1 P14902 1/20 0.33
GAA P10253 1/20 0.32
PKM P14618 1/20 0.32
NPY5R Q15761 1/20 0.32
GRIA4 P48058 1/20 0.31
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30
IKBKB O14920 1/20 0.30
CHUK O15111 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28224025 0.98 EPHX1 (0.50) EPHX1CA2CA1MEN1HTT
SCHEMBL9347611 0.86 EPHX1 (0.39) EPHX1CA2CA1CA7CA13
SCHEMBL15116353 0.86 EPHX1 (0.59) EPHX1CA2CA1MEN1HTT
SCHEMBL1260722 0.84 EPHX1 (0.62) EPHX1CA2CA1MEN1HTT
SCHEMBL12789664 0.84 EPHX1 (0.60) EPHX1CA2CA1MEN1HTT
SCHEMBL28462696 0.82 EPHX1 (0.60) EPHX1CA2CA1MEN1HTT
SCHEMBL21716038 0.82 EPHX1 (0.66) EPHX1CA2CA1MEN1KMT2A
SCHEMBL20860680 0.79 EPHX1 (0.38) EPHX1CA2CA1ALDH1A1CYP2C19
SCHEMBL10029324 0.79 CA2 (0.50) EPHX1CA2CA1MEN1HTT
SCHEMBL28569773 0.78 ALDH1A1 (0.33) EPHX1ALDH1A1CYP2C19GAAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 373 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250260049-A1 FLUORINATED SULFONAMIDE COMPOUNDS FOR ENHANCING ION CONDUCTIVITY OF POLYMER ELECTROLYTES TOYOTA MOTOR ENGINEERING & MANUFACTURING NORTH AMERICA, INC. (US) 2025-08-14 US disclosed
CN-119143836-A Polypeptide cyclization method 广州医科大学 2024-12-17 CN disclosed
EP-4450486-A1 SALT COMPOUND, AND QUENCHER AND PHOTORESIST COMPOSITION COMPRISING SAME Dongjin Semichem Co., Ltd. (KR) 2024-10-23 EP disclosed
US-20240337930-A1 SALT COMPOUND AND QUENCHER, PHOTORESIST COMPOSITION COMPRISING THE SAME DONGJIN SEMICHEM CO., LTD. (KR) 2024-10-10 US disclosed
CN-118488941-A Salt compound, acid diffusion inhibitor containing the same, and photoresist composition 株式会社东进世美肯 2024-08-13 CN disclosed
CN-117430743-A Polymer, photoresist composition including the same, and method of forming pattern using the photoresist composition 三星电子株式会社 2024-01-23 CN disclosed
US-11874601-B2 Resist composition, method of forming resist pattern, compound, and acid diffusion-controlling agent TOKYO OHKA KOGYO CO., LTD. (JP) 2024-01-16 US disclosed
US-11874601-B2 Resist composition, method of forming resist pattern, compound, and acid diffusion-controlling agent TOKYO OHKA KOGYO CO., LTD. (JP) 2024-01-16 US disclosed
US-11835857-B2 Resist composition and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2023-12-05 US disclosed
US-11829068-B2 Resist composition, method of forming resist pattern, compound, and resin TOKYO OHKA KOGYO CO., LTD. (JP) 2023-11-28 US disclosed
EP-2271625-A2 TETRAHYDROISOQUINOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY Abbott GmbH & Co. KG (DE) 2011-01-12 EP disclosed
WO-2010140483-A1 FLUORINE-CONTAINING COMPOUND, FLUORINE-CONTAINING POLYMER COMPOUND, RESIST COMPOSITION, TOP COAT COMPOSITION AND PATTERN FORMATION METHOD セントラル硝子株式会社 (JP) 2010-12-09 WO disclosed
US-20100273739-A1 Aminotetraline Derivatives, Pharmaceutical Composition, Containing Them, and Their Use in Therapy ABBVIE INC. 2010-10-28 US disclosed
US-20100222346-A1 4-BENZYLAMINOQUINOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY ABBVIE DEUTSCHLAND GMBH & CO KG (DE) 2010-09-02 US disclosed
WO-2010092181-A1 HETEROCYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE AS INHIBITORS OF THE GLYCINE TRANSPORTER 1 ABBOTT GMBH & CO. KG (DE) 2010-08-19 WO disclosed
WO-2010092180-A1 Aminotetraline derivatives, pharmaceutical compositions containing them, and their use in therapy ABBOTT GMBH & CO. KG (DE) 2010-08-19 WO disclosed
EP-2178842-A2 4-BENZYLAMINOQUINOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE Abbott GmbH & Co. KG (DE) 2010-04-28 EP disclosed
WO-2009121872-A2 TETRAHYDROISOQUINOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY ABBOTT GMBH & CO. KG (DE) 2009-10-08 WO disclosed
WO-2009024611-A2 4-BENZYLAMINOQUINOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE ABBOTT GMBH & CO. KG (DE) 2009-02-26 WO disclosed
US-6025457-A POLYMERIZABLE IMIDAZOLIUM DERIVATIVE; HEAT RESISTANCE SHIKOKU CHEMICALS CORPORATION (JP) 2000-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11874601-B2 Resist composition, method of forming resist pattern, compound, and acid diffusion-controlling agent MRPS23, MRPS22, SLC11A2 EPHX1 4516/4885CA2 1207/4885CA1 1150/4885
US-20100273739-A1 Aminotetraline Derivatives, Pharmaceutical Composition, Containing Them, and Their Use in Therapy AADAT, GFPT1, BCAT1 EPHX1 2823/4885CA2 807/4885CA1 2571/4885
US-20100222346-A1 4-BENZYLAMINOQUINOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY GDI2, GDI1, NQO2 EPHX1 912/4885CA2 619/4885CA1 4076/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.