Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287467 | 0.79 | POLB (0.36) | ALDH1A1POLBNPC1RAB9AMEN1 | |
| SCHEMBL287683 | 0.79 | NPC1 (0.39) | ALDH1A1POLBNPC1RAB9AMEN1 | |
| SCHEMBL287119 | 0.78 | ALDH1A1 (0.39) | ALDH1A1POLBNPC1RAB9AMEN1 | |
| SCHEMBL287825 | 0.74 | ALDH1A1 (0.34) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL287968 | 0.74 | TDP1 (0.41) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL285705 | 0.73 | ALDH1A1 (0.33) | ALDH1A1POLBMEN1KMT2ALMNA | |
| SCHEMBL12262036 | 0.68 | ALDH1A1 (0.60) | ALDH1A1POLBNPC1RAB9AMEN1 | |
| SCHEMBL287432 | 0.67 | TSHR (0.41) | ALDH1A1POLBNPC1RAB9AMEN1 | |
| SCHEMBL5046549 | 0.65 | ALDH1A1 (0.57) | ALDH1A1POLBNPC1RAB9AMEN1 | |
| SCHEMBL287282 | 0.65 | TDP1 (0.43) | ALDH1A1NPC1RAB9AKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | disclosed |