Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | TPMT | P51580 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SELL | P14151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20202139 | 0.84 | TSHR (0.45) | TSHRALOX15HIF1AHCAR1HCAR2 | |
| SCHEMBL20225494 | 0.84 | TPMT (0.46) | TSHRALOX15HIF1AHCAR1HCAR2 | |
| SCHEMBL11964240 | 0.81 | ALOX15 (0.42) | TSHRALOX15HIF1AHCAR1MAPT | |
| SCHEMBL28304077 | 0.80 | KDM4E (0.56) | TSHRALOX15HIF1ACA12CA1 | |
| SCHEMBL22972017 | 0.77 | PARP1 (0.45) | TSHRLMNAMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL2859980 | 0.77 | ALDH1A1 (0.33) | TSHRALOX15HIF1AHCAR2ALDH1A1 | |
| SCHEMBL17371701 | 0.75 | ALDH1A1 (0.42) | TSHRKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL26189 | 0.73 | CA12 (0.65) | TSHRALOX15HIF1AHCAR1CA12 | |
| SCHEMBL22982 | 0.73 | CA12 (0.65) | TSHRALOX15HIF1AHCAR1CA12 | |
| SCHEMBL336433 | 0.72 | HCAR1 (0.73) | TSHRALOX15HIF1AHCAR1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118930884-A | Fluorine-containing metal organic framework material for methane and nitrogen separation, and preparation method and application thereof | 浙江工业大学 | 2024-11-12 | — | — | CN | claimed |
| CN-110818629-A | Method for synthesizing fluoroisonicotinic acid derivative | 杭州勇诚睿生物科技有限公司 | 2020-02-21 | — | — | CN | claimed |
| US-20260132133-A1 | MACROCYCLIC HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC (US) | 2026-05-14 | — | — | US | disclosed |
| EP-4010330-B1 | QUINOLINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | HIRUNDO BIOSCIENCES (BE) | 2025-10-01 | — | — | EP | disclosed |
| WO-2025109475-A1 | SHP-1 AGONISTS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2025-05-30 | — | — | WO | disclosed |
| EP-4511128-A1 | MACROCYCLIC HETEROCYCLES AND USES THEREOF | Kumquat Biosciences Inc. (US) | 2025-02-26 | — | — | EP | disclosed |
| US-12195465-B2 | Macrocyclic heterocycles and uses thereof | KUMQUAT BIOSCIENCES INC. (US) | 2025-01-14 | — | — | US | disclosed |
| CN-119095849-A | Macrocyclic heterocycles and uses thereof | 金橘生物科技公司 | 2024-12-06 | — | — | CN | disclosed |
| US-12156523-B2 | Plant disease control agent | MMAG CO., LTD. (JP) | 2024-12-03 | — | — | US | disclosed |
| CN-118930884-A | Fluorine-containing metal organic framework material for methane and nitrogen separation, and preparation method and application thereof | 浙江工业大学 | 2024-11-12 | — | — | CN | disclosed |
| US-20240208975-A1 | MACROCYCLIC HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. | 2024-06-27 | — | — | US | disclosed |
| WO-2014060493-A2 | N-(PYRIDIN-2-YL)PYRIMIDIN-4-AMINE DERIVATIVES CONTAINING A SULFONE GROUP | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-04-24 | — | — | WO | disclosed |
| WO-2014060375-A2 | 5-FLUORO-N-(PYRIDIN-2-YL)PYRIDIN-2-AMINE DERIVATIVES CONTAINING A SULFONE GROUP | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-04-24 | — | — | WO | disclosed |
| WO-2010107384-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-09-23 | — | — | WO | disclosed |
| WO-2010107384-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-09-23 | — | — | WO | disclosed |
| US-20100137376-A1 | AMIDE COMPOUND AND METHOD FOR CONTROLLING PLANT DISEASE USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-03 | — | — | US | disclosed |
| EP-2174931-A1 | AMIDE COMPOUND AND METHOD FOR CONTROLLING PLANT DISEASE USING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2010-04-14 | — | — | EP | disclosed |
| EP-0268775-B1 | METHOD FOR PROTECTING PLANTS AGAINST DISEASES | CIBA-GEIGY AG (CH) | 1992-12-23 | — | — | EP | disclosed |
| US-4968344-A | FUNGICIDES, BACTERICIDES | CIBA-GEIGY CORPORATION (US) | 1990-11-06 | — | — | US | disclosed |
| EP-0268775-A1 | Method for protecting plants against diseases | CIBA-GEIGY AG (CH) | 1988-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208975-A1 | MACROCYCLIC HETEROCYCLES AND USES THEREOF | HRAS, KRAS, TP53 | TSHR 2022/4885ALOX15 4767/4885HIF1A 3782/4885 |
| US-12156523-B2 | Plant disease control agent | BROX, ALG1, CTRL | TSHR 4374/4885ALOX15 1387/4885HIF1A 1395/4885 |
| US-20260132133-A1 | MACROCYCLIC HETEROCYCLES AND USES THEREOF | KRAS, HRAS, BCL6 | TSHR 371/4885ALOX15 3716/4885HIF1A 2986/4885 |
| US-12195465-B2 | Macrocyclic heterocycles and uses thereof | HRAS, KRAS, TP53 | TSHR 2022/4885ALOX15 4767/4885HIF1A 3782/4885 |
| US-20100137376-A1 | AMIDE COMPOUND AND METHOD FOR CONTROLLING PLANT DISEASE USING THE SAME | NAAA, NAT1, SAT1 | TSHR 3394/4885ALOX15 1738/4885HIF1A 2136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.