Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Thiobenzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiobenzoic Acid SCHEMBL284148 | 1.00 | CA2 (0.48) | CA2CA4ALDH1A1MAPTL3MBTL1 | |
| Thiobenzoic Acid SCHEMBL6768673 | 0.94 | CA2 (0.48) | CA2CA4ALDH1A1MAPTL3MBTL1 | |
| Thiobenzoic Acid SCHEMBL4056513 | 0.94 | CA2 (0.48) | CA2CA4ALDH1A1MAPTL3MBTL1 | |
| Thiobenzoic Acid SCHEMBL28582374 | 0.94 | CA2 (0.55) | CA2CA4ALDH1A1MAPTL3MBTL1 | |
| Thiobenzoic Acid SCHEMBL6890939 | 0.94 | CA2 (0.48) | CA2CA4ALDH1A1MAPTL3MBTL1 | |
| Thiobenzoic Acid SCHEMBL10423562 | 0.94 | CA2 (0.48) | CA2CA4ALDH1A1MAPTL3MBTL1 | |
| Thiobenzoic Acid SCHEMBL29374102 | 0.94 | CA2 (0.55) | CA2CA4ALDH1A1MAPTL3MBTL1 | |
| Thiobenzoic Acid SCHEMBL20741484 | 0.94 | CA2 (0.48) | CA2CA4ALDH1A1MAPTL3MBTL1 | |
| Thiobenzoic Acid SCHEMBL22721212 | 0.94 | CA2 (0.48) | CA2CA4ALDH1A1MAPTL3MBTL1 | |
| Thiobenzoic Acid SCHEMBL28946274 | 0.94 | CA2 (0.48) | CA2CA4ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112955503-A | Chloroprene rubber composition and vulcanized molded article | 电化株式会社 | 2021-06-11 | — | — | CN | disclosed |
| CN-112912431-A | Chloroprene-unsaturated nitrile copolymer composition and vulcanized molded article | 电化株式会社 | 2021-06-04 | — | — | CN | disclosed |
| CN-112912410-A | Chloroprene-unsaturated nitrile copolymer, chloroprene-unsaturated nitrile copolymer composition, and vulcanized molded article | 电化株式会社 | 2021-06-04 | — | — | CN | disclosed |