Sugi Predict

Sugi Predict / Compounds / SCHEMBL2857202

SCHEMBL2857202

SCHEMBL2857202

CO/C=C(/C(=O)O)c1ccccc1Oc1cc(Oc2ccccc2C)ncn1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 4/20 0.42
▸ MAPT P10636 3/20 0.42
▸ LMNA P02545 2/20 0.42
▸ ALDH1A1 P00352 4/20 0.40
▸ NPC1 O15118 2/20 0.40
▸ RAB9A P51151 2/20 0.40
▸ HTT P42858 2/20 0.40
▸ HSP90AA1 P07900 1/20 0.40
▸ XBP1 P17861 1/20 0.40
▸ MAPK1 P28482 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40
▸ MEN1 O00255 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ TSHR P16473 1/20 0.38
▸ MAP4K4 O95819 1/20 0.36
▸ PTGS2 P35354 1/20 0.36
▸ CYP1A2 P05177 2/20 0.35
▸ CYP2C9 P11712 2/20 0.35
▸ CYP2C19 P33261 2/20 0.35
▸ CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2857209 1.00 SMN1; SMN2 (0.42) SMN1; SMN2MAPTLMNAALDH1A1NPC1
SCHEMBL21858898 1.00 SMN1; SMN2 (0.42) SMN1; SMN2MAPTLMNAALDH1A1NPC1
SCHEMBL203794 0.90 SMN1; SMN2 (0.42) SMN1; SMN2MAPTLMNAALDH1A1NPC1
SCHEMBL6448582 0.90 SMN1; SMN2 (0.42) SMN1; SMN2MAPTLMNAALDH1A1NPC1
SCHEMBL29358657 0.90 SMN1; SMN2 (0.42) SMN1; SMN2MAPTLMNAALDH1A1NPC1
SCHEMBL2857206 0.89 SMN1; SMN2 (0.44) SMN1; SMN2MAPTLMNAALDH1A1NPC1
SCHEMBL2852235 0.88 RAF1 (0.37) SMN1; SMN2MAPTALDH1A1NPC1RAB9A
SCHEMBL2852231 0.88 RAF1 (0.37) SMN1; SMN2MAPTALDH1A1NPC1RAB9A
SCHEMBL29360421 0.88 RAF1 (0.37) SMN1; SMN2MAPTALDH1A1NPC1RAB9A
SCHEMBL28477526 0.87 MEN1 (0.36) SMN1; SMN2MAPTLMNAALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043600-B2 Microbiocidal compounds SYNGENTA CROP PROTECTION AG (CH) 2024-07-23 — — US disclosed
US-12012399-B2 Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives SYNGENTA PARTICIPATIONS AG (CH) 2024-06-18 — — US disclosed
CN-114340374-B Sowing device and method for treating seeds during planting 先正达参股股份有限公司 2024-06-11 — — CN disclosed
CN-112789265-B Microbiocidal compounds 先正达农作物保护股份公司 2024-03-08 — — CN disclosed
US-20240041028-A1 DELIVERY SYSTEM FOR PLANT PROTECTION OMYA INTERNATIONAL AG (CH) 2024-02-08 — — US disclosed
US-11882834-B2 Microbiocidal thiazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2024-01-30 — — US disclosed
EP-4271185-A1 DELIVERY SYSTEM FOR PLANT PROTECTION Omya International AG (CH) 2023-11-08 — — EP disclosed
CN-111303116-B Microbiocidal heterobicyclic derivatives 先正达参股股份有限公司 2023-10-10 — — CN disclosed
CN-111406055-B Microbiocidal thiazole derivatives 先正达参股股份有限公司 2023-09-22 — — CN disclosed
US-11744246-B2 Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide SYNGENTA PARTICIPATIONS AG (CH) 2023-09-05 — — US disclosed
WO-2008005489-A2 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF AVENTIS AGRICULTURE (FR) 2008-01-10 — — WO disclosed
US-7001903-B2 Synergistic insecticidal mixtures BAYER AKTIENGESELLSCHAFT (DE) 2006-02-21 — — US disclosed
US-20050187215-A1 synergistic mixture of certain previously disclosed cyclic ketoenols and agonists or antagonists of nicotinic acetylcholine receptors BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-08-25 — — US disclosed
US-6846777-B2 Synergistic biocidal composition THOR GMBH (DE) 2005-01-25 — — US disclosed
US-20040127520-A1 Synergistic insecticidal mixtures DOW AGROSCIENCES LLC 2004-07-01 — — US disclosed
US-6686387-B2 SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS; PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2004-02-03 — — US disclosed
US-20030199490-A1 Synergistic biocidal composition THOR GMBH (DE) 2003-10-23 — — US disclosed
US-20030092641-A1 Synergistic insecticidal mixtures DOW AGROSCIENCES LLC 2003-05-15 — — US disclosed
US-6444667-B1 OF SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS FOR PROTECTING PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2002-09-03 — — US disclosed
US-5466693-A FOE USE IN THE CULTIVATION OF RICE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-11-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030092641-A1 Synergistic insecticidal mixtures CHRM3, ACHE, CHRM2 SMN1; SMN2 704/4885MAPT 3320/4885LMNA 3444/4885
US-12043600-B2 Microbiocidal compounds MPO, MSR1, PRF1 SMN1; SMN2 3579/4885MAPT 4642/4885LMNA 4247/4885
US-20040127520-A1 Synergistic insecticidal mixtures CHRM3, ACHE, CHRM2 SMN1; SMN2 704/4885MAPT 3320/4885LMNA 3444/4885
US-11882834-B2 Microbiocidal thiazole derivatives MSR1, TLR1, IFNG SMN1; SMN2 3617/4885MAPT 4168/4885LMNA 4274/4885
US-12012399-B2 Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives TLR1, TLR5, IDO1 SMN1; SMN2 4440/4885MAPT 2674/4885LMNA 4252/4885
US-20050187215-A1 synergistic mixture of certain previously disclosed cyclic ketoenols and agonists or antagonists of nicotinic acetylcholine receptors CHRNG, CHRM3, CHRNE SMN1; SMN2 4593/4885MAPT 4170/4885LMNA 4203/4885
US-11744246-B2 Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide PHF20, FUCA1, ZP1 SMN1; SMN2 4536/4885MAPT 3334/4885LMNA 4022/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.