Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857586 | 0.86 | ATR (0.39) | P2RX7ATRMALT1GAAP2RY1 | |
| SCHEMBL2857955 | 0.85 | NPY5R (0.42) | MALT1KEAP1NFE2L2MAPT | |
| SCHEMBL2855775 | 0.84 | P2RY1 (0.44) | P2RX7GAAP2RY1ANO1KDM4E | |
| SCHEMBL2850855 | 0.84 | KEAP1 (0.36) | MALT1RXFP1KEAP1NFE2L2KDM4E | |
| SCHEMBL2850763 | 0.84 | MAPT (0.48) | ATRGAAP2RY1KDM4EMAPT | |
| SCHEMBL2854678 | 0.82 | ATR (0.40) | P2RX7ATRGAAP2RY1ANO1 | |
| SCHEMBL2858606 | 0.81 | P2RY1 (0.47) | GAAP2RY1KDM4EMAPT | |
| SCHEMBL2852553 | 0.81 | MALT1 (0.40) | MALT1KEAP1NFE2L2KDM4EMAPT | |
| SCHEMBL2854492 | 0.80 | MAPT (0.42) | MALT1GAAKDM4EMAPT | |
| SCHEMBL2852401 | 0.80 | L3MBTL1 (0.39) | RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |