Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342313 | 0.84 | ALDH1A1 (0.42) | MMP2TDP1MBOAT4FFAR1ALDH1A1 | |
| SCHEMBL19582086 | 0.80 | MBOAT4 (0.37) | MMP2TDP1MBOAT4ALDH1A1MAPT | |
| SCHEMBL19582083 | 0.80 | MBOAT4 (0.37) | MMP2TDP1MBOAT4ALDH1A1MAPT | |
| SCHEMBL29022647 | 0.80 | GABRA1 (0.41) | FFAR1 | |
| SCHEMBL2308798 | 0.79 | MBOAT4 (0.40) | MMP2MBOAT4PARP2PARP15PARP10 | |
| SCHEMBL28846885 | 0.79 | LMNA (0.40) | MMP2AOC3TDP1MBOAT4PARP2 | |
| SCHEMBL13141087 | 0.78 | MBOAT4 (0.42) | MBOAT4ALDH1A1 | |
| SCHEMBL22557366 | 0.77 | ADRA2A (0.38) | PARP10 | |
| SCHEMBL20582285 | 0.76 | FFAR1 (0.50) | MMP2MBOAT4PARP2PARP1FFAR1 | |
| SCHEMBL17674283 | 0.76 | KDM4E (0.42) | MBOAT4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964684-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117964683-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-112867706-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2021-05-28 | — | — | CN | disclosed |