Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ATF4 | P18848 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
| ▸ | MDH1 | P40925 | 1/20 | 0.42 |
| ▸ | MDH2 | P40926 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28577681 | 0.85 | ATF4 (0.69) | ALDH1A1ATF4 | |
| SCHEMBL21819383 | 0.83 | ATF4 (0.72) | ALDH1A1ATF4L3MBTL1MAPTLMNA | |
| Trifluoroacetic Acid SCHEMBL21819296 | 0.82 | ALDH1A1 (0.53) | ALDH1A1ATF4L3MBTL1MAPTADAMTS4 | |
| SCHEMBL21819450 | 0.81 | ATF4 (0.63) | ALDH1A1ATF4MAPTLMNASLC6A5 | |
| SCHEMBL28587516 | 0.80 | ATF4 (0.72) | ATF4 | |
| SCHEMBL21882376 | 0.77 | ATF4 (0.57) | ALDH1A1ATF4MAPTMDH1MDH2 | |
| SCHEMBL28590128 | 0.74 | ATF4 (0.52) | ALDH1A1ATF4LMNAKMT2A | |
| SCHEMBL16082967 | 0.72 | LMNA (0.71) | ALDH1A1ATF4L3MBTL1MAPTLMNA | |
| Trifluoroacetic Acid SCHEMBL21819314 | 0.71 | ATF4 (0.65) | ALDH1A1ATF4MCHR1 | |
| SCHEMBL21819532 | 0.70 | ATF4 (0.75) | ALDH1A1ATF4L3MBTL1MCHR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112912082-A | Integrated stress pathway inhibitors | 普拉西斯生物技术有限责任公司 | 2021-06-04 | — | — | CN | disclosed |