Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | FABP2 | P12104 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5345949 | 0.82 | ALOX5 (0.47) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL27638158 | 0.81 | GABRA1 (0.44) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL4616721 | 0.80 | S1PR1 (0.44) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL1477690 | 0.77 | GRM5 (0.43) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL26262204 | 0.77 | GABRA1 (0.40) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL31062410 | 0.75 | GABRG2 (0.45) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL12477508 | 0.75 | CYP1A2 (0.59) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9264032 | 0.75 | ALDH1A1 (0.49) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9303383 | 0.74 | PTGS1 (0.42) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2322002 | 0.74 | LMNA (0.46) | PTGS1MEN1KMT2APTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778115-B | Preparation method of flurbiprofen | 山东师范大学 | 2022-08-09 | — | — | CN | claimed |
| CN-112778115-A | Preparation method of flurbiprofen | 山东师范大学 | 2021-05-11 | — | — | CN | claimed |
| CN-114887666-B | Catalyst and application thereof | 山东师范大学 | 2023-12-22 | — | — | CN | disclosed |
| CN-114887666-B | Catalyst and application thereof | 山东师范大学 | 2023-12-22 | — | — | CN | disclosed |
| CN-114887666-A | Catalyst and application thereof | 山东师范大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-114887666-A | Catalyst and application thereof | 山东师范大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-112778115-B | Preparation method of flurbiprofen | 山东师范大学 | 2022-08-09 | — | — | CN | disclosed |
| CN-112778115-B | Preparation method of flurbiprofen | 山东师范大学 | 2022-08-09 | — | — | CN | disclosed |
| CN-112778115-A | Preparation method of flurbiprofen | 山东师范大学 | 2021-05-11 | — | — | CN | disclosed |
| CN-112778115-A | Preparation method of flurbiprofen | 山东师范大学 | 2021-05-11 | — | — | CN | disclosed |