Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855874 | 0.79 | NPC1 (0.35) | FFAR2 | |
| SCHEMBL2857945 | 0.71 | USP30 (0.42) | CCR2FFAR2 | |
| SCHEMBL26656258 | 0.70 | — | — | |
| SCHEMBL25282262 | 0.70 | HRH3 (0.39) | — | |
| SCHEMBL5673331 | 0.64 | RAB9A (0.38) | — | |
| SCHEMBL27868446 | 0.63 | RIPK1 (0.38) | — | |
| SCHEMBL1189042 | 0.63 | HSD17B10 (0.36) | — | |
| SCHEMBL975722 | 0.63 | FFAR2 (0.32) | CCR2FFAR2 | |
| SCHEMBL19205914 | 0.62 | RIPK1 (0.31) | — | |
| SCHEMBL22467749 | 0.62 | RIPK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968957-B1 | SUBSTITUTED THIAZOLES AND THEIR USE FOR PRODUCING DRUGS | GRUENENTHAL GMBH (DE) | 2010-01-20 | — | — | EP | disclosed |
| WO-2007079960-A9 | SUBSTITUTED THIAZOLES AND THEIR USE FOR PRODUCING DRUGS | GRUENENTHAL GMBH (DE) | 2008-10-23 | — | — | WO | disclosed |
| EP-1968957-A1 | SUBSTITUTED THIAZOLES AND THEIR USE FOR PRODUCING DRUGS | Grünenthal GmbH (DE) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007079960-A1 | SUBSTITUTED THIAZOLES AND THEIR USE FOR PRODUCING DRUGS | Grünenthal GmbH (DE) | 2007-07-19 | — | — | WO | disclosed |