Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD4 | P21917 | 3/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 8/20 | 0.49 |
| ▸ | UBE2M | P61081 | 3/20 | 0.49 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854763 | 0.84 | DRD4 (0.50) | DRD2DRD4CNR1CCR2SIGMAR1 | |
| SCHEMBL2858205 | 0.81 | RAB9A (0.49) | CNR1KMT2A | |
| SCHEMBL2853232 | 0.79 | CCR1 (0.48) | KMT2AKDM4E | |
| SCHEMBL2857724 | 0.78 | SIGMAR1 (0.53) | SIGMAR1 | |
| SCHEMBL31616464 | 0.77 | DRD2 (0.73) | DRD2DRD4CNR1CCR2DCUN1D1 | |
| SCHEMBL31616395 | 0.77 | DRD2 (0.73) | DRD2DRD4CNR1CCR2DCUN1D1 | |
| SCHEMBL31616444 | 0.77 | DRD2 (0.73) | DRD2DRD4CNR1CCR2DCUN1D1 | |
| SCHEMBL2856146 | 0.77 | CNR1 (0.53) | CNR1KMT2AKDM4E | |
| SCHEMBL2858063 | 0.77 | MAPT (0.57) | KDM4E | |
| SCHEMBL2854169 | 0.76 | MAPT (0.56) | KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |