Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | KHK | P50053 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25016018 | 0.84 | HTR4 (0.46) | HTR4CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL28598772 | 0.84 | HTR4 (0.44) | HTR4EPHX1CHRM1ACSS2BCHE | |
| SCHEMBL21822542 | 0.83 | HTR4 (0.44) | HTR4CHRM1ACSS2HDAC3HDAC4 | |
| SCHEMBL28593853 | 0.79 | HTR6 (0.44) | HTR4CHRM1ACSS2 | |
| SCHEMBL28916206 | 0.78 | ALDH1A1 (0.54) | CNR1CNR2 | |
| SCHEMBL10144838 | 0.71 | HDAC3 (0.67) | HTR4CHRM1ACSS2NAMPTHDAC3 | |
| SCHEMBL21822628 | 0.67 | F10 (0.55) | — | |
| SCHEMBL21822470 | 0.66 | F10 (0.43) | HTR4ACSS2HDAC3HDAC4HDAC1 | |
| SCHEMBL21822469 | 0.66 | F10 (0.43) | HTR4ACSS2HDAC3HDAC4HDAC1 | |
| SCHEMBL25017546 | 0.66 | F10 (0.43) | HTR4ACSS2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |