Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | F10 | P00742 | 4/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28593853 | 0.86 | HTR6 (0.44) | HTR4PPARGBRD4F10CHRM1 | |
| SCHEMBL28582228 | 0.84 | HTR4 (0.45) | HTR4EPHX1CHRM1ACSS2BCHE | |
| SCHEMBL21822628 | 0.83 | F10 (0.55) | F10 | |
| SCHEMBL21822469 | 0.82 | F10 (0.43) | HTR4PPARGBRD4F10ACSS2 | |
| SCHEMBL21822470 | 0.82 | F10 (0.43) | HTR4PPARGBRD4F10ACSS2 | |
| SCHEMBL25017546 | 0.82 | F10 (0.43) | HTR4PPARGBRD4F10ACSS2 | |
| SCHEMBL28594363 | 0.76 | F10 (0.44) | PPARGEPHX1F10CCR2 | |
| SCHEMBL25017427 | 0.75 | HTR4 (0.43) | HTR4PPARGF10 | |
| SCHEMBL28598807 | 0.74 | F10 (0.42) | HTR4F10ACSS2 | |
| SCHEMBL25016018 | 0.72 | HTR4 (0.46) | HTR4PPARGCHRM1ACSS2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |