Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28600151 | 0.86 | KDM4E (0.48) | XDHKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL28589920 | 0.85 | XDH (0.51) | XDHKDM4EALDH1A1SMN1; SMN2IDO1 | |
| SCHEMBL28587011 | 0.81 | XDH (0.45) | XDHKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL28586213 | 0.81 | ALDH1A1 (0.43) | XDHKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL28587007 | 0.81 | NPC1 (0.68) | XDHKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL28570870 | 0.81 | XDH (0.54) | XDHKDM4EALDH1A1IDO1PKM | |
| SCHEMBL28589457 | 0.78 | XDH (0.43) | XDHKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL28699403 | 0.76 | XDH (0.47) | XDHKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL28916533 | 0.75 | XDH (0.53) | XDHPTGER1 | |
| SCHEMBL28589653 | 0.73 | XDH (0.42) | XDHKDM4EALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004208-A | Compound for inhibiting xanthine oxidase activity and preparation method and application thereof | 沈阳药科大学 | 2021-06-22 | — | — | CN | claimed |
| CN-113004208-A | Compound for inhibiting xanthine oxidase activity and preparation method and application thereof | 沈阳药科大学 | 2021-06-22 | — | — | CN | disclosed |