Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20180485 | 0.83 | SLC6A2 (0.34) | ALDH1A1 | |
| SCHEMBL20889893 | 0.82 | — | — | |
| SCHEMBL20648805 | 0.80 | ADRA2C (0.31) | — | |
| SCHEMBL21448024 | 0.74 | SLC6A3 (0.41) | BRD4ALDH1A1 | |
| SCHEMBL21388387 | 0.73 | SLC6A2 (0.35) | — | |
| SCHEMBL28591647 | 0.73 | TAS1R3 (0.38) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL28597593 | 0.72 | — | — | |
| SCHEMBL3877662 | 0.71 | BRD4 (0.41) | BRD4ALDH1A1 | |
| SCHEMBL28604430 | 0.68 | PNMT (0.33) | — | |
| SCHEMBL20889896 | 0.68 | PABPC1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166139-A | Pyrrolo [2,3-b ] pyridines as HPK1 inhibitors and uses thereof | 百济神州有限公司 | 2021-07-23 | — | — | CN | disclosed |