SCHEMBL28587764

SCHEMBL28587764

O=C(Cl)N(Cl)c1ccccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
POLB P06746 2/20 0.38
TSHR P16473 2/20 0.38
LMNA P02545 1/20 0.38
GPBAR1 Q8TDU6 1/20 0.35
KMT2A Q03164 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
ESR1 P03372 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
BCL2A1 Q16548 1/20 0.34
MEN1 O00255 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CYP1A2 P05177 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6002883 0.83 CES2 (0.41) ALDH1A1CES2CES1POLBTSHR
SCHEMBL665305 0.83 ALDH1A1 (0.45) ALDH1A1CES2CES1POLBTSHR
SCHEMBL29524083 0.81 GAA (0.41) ALDH1A1CES2CES1POLBTSHR
SCHEMBL3157322 0.81 GAA (0.41) ALDH1A1CES2CES1POLBTSHR
SCHEMBL4199099 0.81 CES2 (0.40) ALDH1A1CES2CES1POLBTSHR
SCHEMBL465872 0.78 POLB (0.40) ALDH1A1CES2CES1POLBTSHR
SCHEMBL30936965 0.77 GPBAR1 (0.47) ALDH1A1CES2CES1POLBTSHR
SCHEMBL20560161 0.77 ALDH1A1 (0.47) ALDH1A1CES2CES1GPBAR1KMT2A
SCHEMBL28749055 0.76 MEN1 (0.41) ALDH1A1CES2CES1POLBKMT2A
SCHEMBL11502164 0.76 BCL2A1 (0.40) ALDH1A1CES2CES1POLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119139353-A Pharmaceutical composition and cosmetic composition 爱平世股份有限公司 2024-12-17 CN disclosed
CN-112996524-B Pharmaceutical composition and cosmetic composition 爱平世股份有限公司 2024-10-22 CN disclosed
CN-112996524-A Pharmaceutical composition and cosmetic composition 爱平世股份有限公司 2021-06-18 CN disclosed