SCHEMBL665305

SCHEMBL665305

O=C(O)N(Cl)c1ccccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
POLB P06746 2/20 0.39
TSHR P16473 2/20 0.38
LMNA P02545 1/20 0.38
AKR1B1 P15121 1/20 0.38
BCL2A1 Q16548 1/20 0.37
ERCC5 P28715 1/20 0.36
FEN1 P39748 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28587764 0.83 ALDH1A1 (0.41) ALDH1A1CES2CES1KMT2AMEN1
SCHEMBL6002883 0.83 CES2 (0.41) ALDH1A1CES2CES1KMT2AMEN1
SCHEMBL3157322 0.81 GAA (0.41) ALDH1A1CES2CES1KMT2AMEN1
SCHEMBL29524083 0.81 GAA (0.41) ALDH1A1CES2CES1KMT2AMEN1
SCHEMBL4199099 0.81 CES2 (0.40) ALDH1A1CES2CES1KMT2AMEN1
Bicarbonate SCHEMBL29118429 0.80 ALDH1A1 (0.46) ALDH1A1CES2CES1KMT2AMEN1
SCHEMBL465872 0.78 POLB (0.40) ALDH1A1CES2CES1KMT2AMEN1
SCHEMBL4021117 0.77 ALDH1A1 (0.43) ALDH1A1CES2CES1KMT2AMEN1
SCHEMBL1820107 0.77 POLB (0.50) ALDH1A1CES2CES1POLBTSHR
SCHEMBL30927812 0.77 ALDH1A1 (0.52) ALDH1A1POLBTSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12281104-B2 Process for the production of ethyl 3-amino-1-[(3R,4S)-4-cyanotetrahydropyran-3-yl]pyrazole-4-carboxylate through chiral separation of a racemic mixture INTERVET INC. (US) 2025-04-22 US disclosed
US-20220204483-A1 Process for the Production of Ethyl 3-Amino-1-[(3R,4S)-4-Cyanotetrahydropyran-3-YL]pyrazole-4-Carboxylate Through Chiral Separation of a Racemic Mixture INTERVET INC. (US) 2022-06-30 US disclosed
EP-3991835-A1 TRIGLYCERIDE ANALYSIS METHOD, OIL AND FAT SORTING METHOD, AND TRIGLYCERIDE PRODUCTION METHOD The Nisshin OilliO Group, Ltd. (JP) 2022-05-04 EP disclosed
WO-2019194127-A1 METHOD FOR ANALYZING TRIGLYCERIDE, METHOD FOR SEPARATING OIL AND FAT, AND METHOD FOR MANUFACTURING TRIGLYCERIDE 日清オイリオグループ株式会社 2019-10-10 WO disclosed
US-9149791-B2 Water-soluble carbohydrate polyethers TRGel, LLC (US) 2015-10-06 US disclosed
US-8642502-B2 Reversible gel-forming compositions for controlled delivery of bioactive substances TRGel, LLC (US) 2014-02-04 US disclosed
US-20120087891-A1 Reversible Gel-forming Compositions for Controlled Delivery of Bioactive Substances GORKOVENKO ALEXANDER A (US) 2012-04-12 US disclosed
US-20120046435-A1 Water-Soluble Carbohydrate Polyethers GORKOVENKO ALEXANDER A (US) 2012-02-23 US disclosed
US-7994092-B2 Carbohydrate polyethers for chromatographic media TRGel, LLC (US) 2011-08-09 US disclosed
US-20090233791-A1 Carbohydrate Polyethers for Chromatographic Media GORKOVENKO ALEXANDER A 2009-09-17 US disclosed
US-20090008329-A1 Separating agent for enantiomeric isomers DAICEL CHEMICAL INDUSTRIES, LTD. 2009-01-08 US disclosed
US-5489387-A Separation agent comprising acyl- or carbamoyl-substituted polysaccharide DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1996-02-06 US disclosed
US-5415780-A Separation agent comprising acyl- or carbamoyl-substituted polysaccharide DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1995-05-16 US disclosed
US-5368737-A Resolution DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1994-11-29 US disclosed
US-5229002-A Separation of optical isomers, cellulose esterified with phenylazobenzoic acid DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1993-07-20 US disclosed
US-5137638-A Mixture of orticla isomers; cellulose tricinnamate DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1992-08-11 US disclosed
US-5075009-A Optical resolution of racemic mixtures using a cellulose tris-4-biphenyl carboxylate DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1991-12-24 US disclosed
US-5017290-A Chromatography DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1991-05-21 US disclosed
US-4966694-A CELLULOSE TRI-BETA-NAPHTHOATE; OPTICAL RESOLUTIONS DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1990-10-30 US disclosed
US-4879038-A Separation agent comprising acyl- or carbamoyl-substituted polysaccharide DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1989-11-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12281104-B2 Process for the production of ethyl 3-amino-1-[(3R,4S)-4-cyanotetrahydropyran-3-yl]pyrazole-4-carboxylate through chiral separation of a racemic mixture CYP3A4, CYP4B1, ACMSD ALDH1A1 457/4885CES2 574/4885CES1 159/4885
US-20120087891-A1 Reversible Gel-forming Compositions for Controlled Delivery of Bioactive Substances PGF, CEL, F12 ALDH1A1 2015/4885CES2 480/4885CES1 543/4885
US-20220204483-A1 Process for the Production of Ethyl 3-Amino-1-[(3R,4S)-4-Cyanotetrahydropyran-3-YL]pyrazole-4-Carboxylate Through Chiral Separation of a Racemic Mixture CYP3A4, CYP4B1, ACMSD ALDH1A1 457/4885CES2 574/4885CES1 159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.