SCHEMBL2858795

SCHEMBL2858795

O=C1OC(Cc2ccccc2)C(=O)OC1Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CTRB1 P17538 1/20 0.52
FASN P49327 1/20 0.50
F2 P00734 2/20 0.46
PRSS1 P07477 2/20 0.46
GRM2 Q14416 1/20 0.43
TLR9 Q9NR96 1/20 0.42
EP300 Q09472 1/20 0.40
MAOB P27338 1/20 0.40
MDM2 Q00987 4/20 0.39
CES2 O00748 1/20 0.39
TSHR P16473 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7629569 0.98 CTRB1 (0.53) CTRB1FASNF2PRSS1GRM2
SCHEMBL4347938 0.89 CTRB1 (0.44) CTRB1FASNF2PRSS1GRM2
SCHEMBL461037 0.89 CTRB1 (0.44) CTRB1FASNF2PRSS1GRM2
SCHEMBL19447203 0.89 FASN (0.58) CTRB1FASNF2PRSS1GRM2
SCHEMBL13223295 0.85 CTRB1 (0.47) CTRB1FASNF2PRSS1GRM2
SCHEMBL15178886 0.83 CTRB1 (0.40) CTRB1FASNF2PRSS1GRM2
SCHEMBL20308653 0.82 F2 (0.44) CTRB1FASNF2PRSS1GRM2
SCHEMBL5501059 0.79 CTRB1 (0.42) CTRB1FASNF2PRSS1GRM2
SCHEMBL24163244 0.78 CAPN1 (0.47)
SCHEMBL13311356 0.77 PARP1 (0.38) CTRB1FASNF2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242491-A1 DIMERS FROM BIOREACHABLE MOLECULES AS COPOLYMERS ZYMERGEN INC. (US) 2023-08-03 US disclosed
US-10314913-B2 Polylactide compositions and uses thereof UNIVERSITY OF GENEVA (CH) 2019-06-11 US disclosed
US-10314913-B2 Polylactide compositions and uses thereof UNIVERSITY OF GENEVA (CH) 2019-06-11 US disclosed
US-20180271984-A1 POLYLACTIDE COMPOSITIONS AND USES THEREOF UNIVERSITY OF GENEVA (CH) 2018-09-27 US disclosed
EP-3339348-A1 POLYLACTIDE COMPOSITIONS AND USES THEREOF Universite De Geneve (CH) 2018-06-27 EP disclosed
EP-3339348-A1 POLYLACTIDE COMPOSITIONS AND USES THEREOF Universite De Geneve (CH) 2018-06-27 EP disclosed
US-9925267-B2 Polylactide compositions and uses thereof UNIVERSITY OF GENEVA (CH) 2018-03-27 US disclosed
US-9925267-B2 Polylactide compositions and uses thereof UNIVERSITY OF GENEVA (CH) 2018-03-27 US disclosed
US-9925267-B2 Polylactide compositions and uses thereof UNIVERSITY OF GENEVA (CH) 2018-03-27 US disclosed
EP-1883665-B1 POLYLACTIDE COMPOSITIONS AND USES THEREOF UNIV GENEVE (CH) 2017-10-11 EP disclosed
EP-1758948-B1 POLYHYDROXYALKANOIC ACID HAVING VINYL, ESTER, CARBOXYL OR SULFONIC ACID GROUP AND PRODUCING METHOD THEREFOR CANON KK (JP) 2009-05-13 EP disclosed
US-7465779-B2 Polyhydroxyalkanoate having vinyl group, ester group, carboxyl group and sulfonic acid group, and production method thereof CANON KABUSHIKI KAISHA (JP) 2008-12-16 US disclosed
EP-1281766-B1 Process for producing polyester, process for producing substituted alpha-hydroxy acid, and Clostridium beijerinckii strain HICA432 CANON KK (JP) 2008-06-04 EP disclosed
US-20080064828-A1 Polyhydroxyalkanoic Acid Having Vinyl, Ester, Carboxyl or Sulfonic Acid Group and Producing Method Therefor CANON KABUSHIKI KAISHA (JP) 2008-03-13 US disclosed
EP-1883665-A2 POLYLACTIDE COMPOSITIONS AND USES THEREOF UNIVERSITE DE GENEVE (CH) 2008-02-06 EP disclosed
US-7273734-B2 Process for producing a polyester CANON KABUSHIKI KAISHA (JP) 2007-09-25 US disclosed
US-7273734-B2 Process for producing a polyester CANON KABUSHIKI KAISHA (JP) 2007-09-25 US disclosed
WO-2007012979-A2 POLYLACTIDE COMPOSITIONS AND USES THEREOF UNIVERSITE DE GENEVE (US) 2007-02-01 WO disclosed
WO-2007012979-A2 POLYLACTIDE COMPOSITIONS AND USES THEREOF UNIVERSITE DE GENEVE (US) 2007-02-01 WO disclosed
US-20060247414-A1 Polyhydroxyalkanoate having vinyl group, ester group, carboxyl group and sulfonic acid group, and production method thereof CANON KABUSHIKI KAISHA (JP) 2006-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10314913-B2 Polylactide compositions and uses thereof LPXN, PUF60, DDOST CTRB1 1787/4885FASN 298/4885F2 2177/4885
US-20080064828-A1 Polyhydroxyalkanoic Acid Having Vinyl, Ester, Carboxyl or Sulfonic Acid Group and Producing Method Therefor FAR1, ACSL4, ACAD11 CTRB1 3279/4885FASN 12/4885F2 2624/4885
US-20230242491-A1 DIMERS FROM BIOREACHABLE MOLECULES AS COPOLYMERS HDHD5, HAO2, ALAD CTRB1 2087/4885FASN 763/4885F2 189/4885
US-20180271984-A1 POLYLACTIDE COMPOSITIONS AND USES THEREOF LPXN, PUF60, DDOST CTRB1 1787/4885FASN 298/4885F2 2177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.