Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | CTSG | P08311 | 3/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.42 |
| ▸ | CMA1 | P23946 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755236 | 0.78 | TSHR (0.41) | ALDH1A1CES1MEN1KMT2A | |
| SCHEMBL8758263 | 0.75 | PRSS1 (0.47) | PRSS1CTSGCTRB1CMA1ALDH1A1 | |
| SCHEMBL11642274 | 0.72 | HDAC2 (0.62) | ALDH1A1HDAC2MEN1KMT2A | |
| SCHEMBL4279863 | 0.71 | TSHR (0.48) | ALDH1A1CES2CES1MEN1KMT2A | |
| SCHEMBL8092296 | 0.71 | CES2 (0.53) | NAAACES2CES1 | |
| SCHEMBL32074 | 0.70 | CES2 (0.54) | NAAACES2CES1 | |
| SCHEMBL7096425 | 0.70 | CES2 (0.54) | NAAACES2CES1 | |
| SCHEMBL3084634 | 0.70 | CES2 (0.54) | NAAACES2CES1 | |
| SCHEMBL3675571 | 0.69 | PRSS1 (0.46) | PRSS1CTSGCTRB1CMA1ALDH1A1 | |
| SCHEMBL5178120 | 0.69 | PTGS2 (0.57) | ALDH1A1NAAACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |