Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4279863 | 0.80 | TSHR (0.48) | TSHRKMT2ANPC1MEN1SRC | |
| SCHEMBL28588564 | 0.78 | PRSS1 (0.42) | KMT2AMEN1ALDH1A1CES1 | |
| SCHEMBL9223639 | 0.75 | PGR (0.53) | KMT2ANPC1MEN1SMN1; SMN2PGR | |
| SCHEMBL1356223 | 0.70 | TSHR (0.48) | TSHRKMT2AMEN1SRCSMN1; SMN2 | |
| SCHEMBL6576791 | 0.69 | TSHR (0.56) | TSHRKMT2ANPC1MEN1SRC | |
| Benzil SCHEMBL1923895 | 0.68 | CES2 (0.54) | KMT2ANPC1MEN1SMN1; SMN2PGR | |
| SCHEMBL25336398 | 0.68 | KLK7 (0.56) | TSHRKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9783633 | 0.68 | ALDH1A1 (0.55) | TSHRKMT2ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL755996 | 0.68 | ESRRB (0.42) | TSHRKMT2ANPC1SRCSMN1; SMN2 | |
| SCHEMBL457034 | 0.68 | TSHR (0.54) | TSHRKMT2ANPC1MEN1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899015-B1 | COMPOSITION WITH TIGHT CAPSULES CONTAINING A SUNSCREEN AGENT | DSM IP ASSETS BV (NL) | 2012-03-21 | — | — | EP | claimed |