SCHEMBL28592124

SCHEMBL28592124

[c]1cccc(-c2ccccc2)c1-c1ccncc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.50
ALDH1A1 P00352 2/20 0.42
MAPT P10636 1/20 0.42
TSHR P16473 1/20 0.42
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
AURKA O14965 1/20 0.42
CDK1 P06493 1/20 0.42
LYN P07948 1/20 0.42
PIM1 P11309 1/20 0.42
FGFR1 P11362 1/20 0.42
PRKACA P17612 1/20 0.42
RPS6KB1 P23443 1/20 0.42
CDK2 P24941 1/20 0.42
MARK3 P27448 1/20 0.42
AKT1 P31749 1/20 0.42
GSK3B P49841 1/20 0.42
RPS6KA3 P51812 1/20 0.42
PRKCZ Q05513 1/20 0.42
PRKCD Q05655 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28598863 1.00 NOTUM (0.50) NOTUMALDH1A1MAPTTSHRHTT
SCHEMBL185890 0.88 ALDH1A1 (0.41) ALDH1A1MAPK1
SCHEMBL4621655 0.84 ALDH1A1 (0.39) ALDH1A1MAPTHTTSMN1; SMN2NPC1
SCHEMBL28592408 0.82 CYP2A6 (0.47) ALDH1A1MAPTTSHRHTTSMN1; SMN2
SCHEMBL9958033 0.82 ALDH1A1 (0.47) ALDH1A1MAPTTSHRHTTSMN1; SMN2
SCHEMBL9162397 0.80 KDM4E (0.45) SMN1; SMN2NPC1RAB9AKDM4EMAPK14
SCHEMBL7754417 0.80 ALDH1A1 (0.38) ALDH1A1MAPTHTTSMN1; SMN2NPC1
SCHEMBL28716480 0.78 CYP1A2 (0.50) ALDH1A1TSHRHTTSMN1; SMN2NPC1
SCHEMBL9559722 0.78 PTGS2 (0.40) ALDH1A1MAPTADORA2AADORA1MAPK14
SCHEMBL4502612 0.77 CYP19A1 (0.39) NOTUMALDH1A1MAPTTSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed