Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185890 | 0.91 | ALDH1A1 (0.41) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL4621655 | 0.87 | ALDH1A1 (0.39) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL18096755 | 0.82 | ALDH1A1 (0.54) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL28598863 | 0.80 | NOTUM (0.50) | ALDH1A1MAPK1NPC1MAPTHTT | |
| SCHEMBL28716480 | 0.80 | CYP1A2 (0.50) | ALDH1A1CYP2A6PTGS2GAAMEN1 | |
| SCHEMBL9559722 | 0.80 | PTGS2 (0.40) | ALDH1A1HSD17B10HPGDBCL2L1PTGS2 | |
| SCHEMBL28592124 | 0.80 | NOTUM (0.50) | ALDH1A1MAPK1NPC1MAPTHTT | |
| SCHEMBL668822 | 0.79 | ALDH1A1 (0.42) | ALDH1A1HSD17B10HPGDMAPK1HDAC8 | |
| SCHEMBL9559797 | 0.79 | PTGS2 (0.39) | BCL2L1PTGS2MEN1MAPTKMT2A | |
| SCHEMBL4819516 | 0.79 | MEN1 (0.35) | ALDH1A1HSD17B10MAPK1MEN1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066229-A1 | OLIGOMERIZATION OF PROPYLENE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-01-10 | — | — | EP | disclosed |
| US-6063881-A | USING COBALT COMPLEXES OF PYRIDINEBIS(IMINES) AS CATALYSTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-05-16 | — | — | US | disclosed |
| WO-1999051550-A1 | OLIGOMERIZATION OF PROPYLENE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-10-14 | — | — | WO | disclosed |
| US-4536400-A | VIRICIDES | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1985-08-20 | — | — | US | disclosed |