SCHEMBL185890

SCHEMBL185890

[c]1cccc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
HSD17B10 Q99714 2/20 0.41
HPGD P15428 1/20 0.41
BCL2L1 Q07817 1/20 0.41
CYP2A6 P11509 1/20 0.41
MAPK1 P28482 1/20 0.41
BACE1 P56817 1/20 0.37
DPP4 P27487 1/20 0.37
HDAC4 P56524 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
BCAT2 O15382 1/20 0.34
CASP3 P42574 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
PTGS2 P35354 1/20 0.33
MGLL Q99685 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4621655 0.96 ALDH1A1 (0.39) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL7754417 0.91 ALDH1A1 (0.38) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL28592124 0.88 NOTUM (0.50) ALDH1A1MAPK1
SCHEMBL28598863 0.88 NOTUM (0.50) ALDH1A1MAPK1
SCHEMBL9559722 0.88 PTGS2 (0.40) ALDH1A1HSD17B10HPGDBCL2L1PTGS2
SCHEMBL28716480 0.88 CYP1A2 (0.50) ALDH1A1CYP2A6PTGS2
SCHEMBL9559797 0.87 PTGS2 (0.39) BCL2L1PTGS2
SCHEMBL18221903 0.86 ALDH1A1 (0.30) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL3327939 0.86 MAOA (0.38) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL7703864 0.85 GSTP1 (0.49) PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4490 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4401536-A1 ORGANIC LIGHT-EMITTING DEVICE LG Chem, Ltd. (KR) 2024-07-17 EP claimed
US-20240237518-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-07-11 US claimed
US-20240215441-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-06-27 US claimed
US-20240206332-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-06-20 US claimed
US-20240206207-A1 ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-06-20 US claimed
WO-2024128844-A1 ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2024-06-20 WO claimed
US-20240196636-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-06-13 US claimed
US-20240196738-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2024-06-13 US claimed
EP-3862350-B1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME LG CHEMICAL LTD (KR) 2024-06-12 EP claimed
WO-2024117762-A1 ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2024-06-06 WO claimed
WO-1996003376-A1 1H-INDOLE-1-FUNCTIONAL sPLA2 INHIBITORS ELI LILLY AND COMPANY (US) 1996-02-08 WO claimed
WO-1996003120-A1 INDENE sPLA2 INHIBITORS ELI LILLY AND COMPANY (US) 1996-02-08 WO claimed
WO-1996003383-A1 INDOLIZINE sPLA2 INHIBITORS ELI LILLY AND COMPANY (US) 1996-02-08 WO claimed
US-5489495-A Electrophotographic photoconductor and diamine compounds for use in the same RICHOH COMPANY, LTD. (JP) 1996-02-06 US claimed
EP-0675110-A1 1H-Indole-3-glyoxylamide sPLA2 inhibitors ELI LILLY AND COMPANY (US) 1995-10-04 EP claimed
WO-1993021192-A1 PROCESS FOR THE HYDROGENATION OF ARYL PHOSPHINES AND PRODUCTS OBTTAINED THEREFROM RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1993-10-28 WO claimed
EP-0103095-B1 DICHROIC MATERIAL CONTAINING ANTHRAQUINONE DYES BAYER AG (DE) 1990-08-29 EP claimed
EP-0187329-B1 CHROMOGENIC 3,1-BENZOXAZINES BAYER AG (DE) 1989-03-08 EP claimed
EP-0187329-A1 Chromogenic 3,1-benzoxazines BAYER AG (DE) 1986-07-16 EP claimed
EP-0103095-A2 Dichroic material containing anthraquinone dyes BAYER AG (DE) 1984-03-21 EP claimed