Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 4/20 | 0.40 |
| ▸ | THRA | P10827 | 3/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 4/20 | 0.38 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | BAX | Q07812 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713613 | 0.90 | THRA (0.39) | NPC1POLBCYP2C9RAB9ATHRB | |
| SCHEMBL9713890 | 0.89 | BACE1 (0.48) | NPC1POLBRAB9ABACE1 | |
| SCHEMBL2859474 | 0.89 | BACE1 (0.47) | BACE1PELI1 | |
| SCHEMBL9817006 | 0.88 | LMNA (0.44) | NPC1RAB9ABACE1LTA4H | |
| SCHEMBL9816997 | 0.87 | LTA4H (0.42) | THRBTHRABACE1GSTP1LTA4H | |
| SCHEMBL9713278 | 0.86 | CNR1 (0.45) | THRBTHRALTA4H | |
| SCHEMBL9816992 | 0.86 | HDAC8 (0.41) | NPC1POLBRAB9ABACE1LTA4H | |
| SCHEMBL9816990 | 0.85 | KIF11 (0.43) | BACE1PELI1 | |
| SCHEMBL9713335 | 0.82 | ESR1 (0.51) | NPC1POLBCYP2C9RAB9ATHRB | |
| SCHEMBL9713951 | 0.79 | KIF11 (0.47) | POLBBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151531-A | DIHYDRIC PHENOLS | IDEMITSU KOSAN CO., LTD. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0249963-B1 | POLYCARBONATES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-04-22 | — | — | EP | disclosed |
| EP-0277627-B1 | POLYFORMAL RESINS AND PROCESS FOR PRODUCING SAID RESINS | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1991-10-23 | — | — | EP | disclosed |
| US-4892924-A | Polycarbonate containing compound from bis(3-phenyl-4-hydroxyphenyl) | IDEMITSU KOSAN CO., LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| US-4801679-A | Polyformal resin and process for producing said resin | IDEMITSU KOSAN CO., LTD. (JP) | 1989-01-31 | — | — | US | disclosed |
| EP-0277627-A1 | Polyformal resins and process for producing said resins | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1988-08-10 | — | — | EP | disclosed |
| EP-0249963-A2 | Polycarbonates | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1987-12-23 | — | — | EP | disclosed |