SCHEMBL9817006

SCHEMBL9817006

CCOc1ccc(C(CC)(c2ccc(O)c(-c3ccccc3)c2)c2ccc(O)c(-c3ccccc3)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
GAA P10253 1/20 0.44
MAPK10 P53779 1/20 0.44
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
GPR55 Q9Y2T6 1/20 0.41
LTA4H P09960 1/20 0.41
KDM4E B2RXH2 1/20 0.40
NPC1 O15118 1/20 0.40
ALDH1A1 P00352 1/20 0.40
TP53 P04637 1/20 0.40
HPGD P15428 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
KIF11 P52732 1/20 0.39
ESR1 P03372 1/20 0.39
HCRTR1 O43613 1/20 0.39
HCRTR2 O43614 1/20 0.39
BACE1 P56817 2/20 0.39
ADORA3 P0DMS8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9816992 0.90 HDAC8 (0.41) GAALTA4HNPC1ALDH1A1RAB9A
SCHEMBL9816984 0.90 LMNA (0.42) LMNAGAAMAPK10CNR1CNR2
SCHEMBL9713890 0.88 BACE1 (0.48) LMNACNR1CNR2KDM4ENPC1
SCHEMBL9713495 0.88 NPC1 (0.40) LTA4HNPC1RAB9ABACE1
SCHEMBL9817071 0.88 LMNA (0.41) LMNAGAAMAPK10CNR1CNR2
SCHEMBL2859474 0.87 BACE1 (0.47) CNR1CNR2ALDH1A1HPGDKIF11
SCHEMBL9816982 0.87 CNR1 (0.42) LMNAGAAMAPK10CNR1CNR2
SCHEMBL9713538 0.85 ESR1 (0.48) LMNAGAAMAPK10CNR1CNR2
SCHEMBL9816990 0.83 KIF11 (0.43) CNR1CNR2ALDH1A1HPGDKIF11
SCHEMBL16429141 0.81 GAA (0.56) LMNAGAAMAPK10CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0277627-B1 POLYFORMAL RESINS AND PROCESS FOR PRODUCING SAID RESINS IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-10-23 EP disclosed
US-4801679-A Polyformal resin and process for producing said resin IDEMITSU KOSAN CO., LTD. (JP) 1989-01-31 US disclosed
EP-0277627-A1 Polyformal resins and process for producing said resins IDEMITSU KOSAN COMPANY LIMITED (JP) 1988-08-10 EP disclosed