Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.37 |
| ▸ | RELA | Q04206 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28752013 | 0.80 | ALDH1A1 (0.41) | CRHBPCRHR2ALDH1A1MAPK1NPC1 | |
| SCHEMBL4572727 | 0.79 | ALDH1A1 (0.38) | ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4572739 | 0.77 | CRHBP (0.43) | CRHBPCRHR2ALDH1A1MAPK1NPC1 | |
| SCHEMBL28595147 | 0.75 | TDP1 (0.32) | — | |
| SCHEMBL16115917 | 0.73 | NPC1 (0.41) | ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13681168 | 0.73 | ALDH1A1 (0.43) | CRHBPCRHR2ALDH1A1MAPK1NPC1 | |
| SCHEMBL4572736 | 0.73 | ALDH1A1 (0.45) | CRHBPCRHR2ALDH1A1MAPK1NPC1 | |
| SCHEMBL26310616 | 0.73 | ALDH1A1 (0.45) | CRHBPCRHR2ALDH1A1MAPK1NPC1 | |
| SCHEMBL28864155 | 0.72 | ALDH1A1 (0.43) | ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24050315 | 0.71 | ALDH1A1 (0.43) | CRHBPCRHR2ALDH1A1MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080303019-A1 | Side Chain-Containing Type Organic Silane Compound, Thin Film Transistor and Method of Producing Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080303019-A1 | Side Chain-Containing Type Organic Silane Compound, Thin Film Transistor and Method of Producing Thereof | CBX3, SOS1, AOX1 | CRHBP 4466/4885CRHR2 3209/4885ALDH1A1 425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.