Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP2 | P42575 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6462907 | 0.98 | LMNA (0.38) | LMNATHRBL3MBTL1 | |
| Thiocyanic Acid SCHEMBL6466470 | 0.86 | LMNA (0.34) | LMNA | |
| Hydrochloric Acid SCHEMBL28526124 | 0.77 | — | — | |
| SCHEMBL3755632 | 0.76 | THRB (0.35) | LMNATHRBL3MBTL1 | |
| SCHEMBL4894909 | 0.74 | ALDH1A1 (0.30) | — | |
| SCHEMBL1598299 | 0.70 | — | — | |
| SCHEMBL28419360 | 0.68 | PPARA (0.32) | LMNAL3MBTL1MEN1KMT2ASMN1; SMN2 | |
| Bromide SCHEMBL10898857 | 0.67 | L3MBTL1 (0.31) | L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9634623 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL3908734 | 0.66 | ALDH1A1 (0.32) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110408278-B | Intrinsic functional coating and preparation and application thereof | 上海富元塑胶科技有限公司 | 2021-06-04 | — | — | CN | disclosed |