Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11974293 | 0.76 | MAOB (0.51) | CYP19A1MAOBPTPN1ALDH1A1KDM4E | |
| SCHEMBL28990300 | 0.75 | LOXL2 (0.36) | LOXL2MAOBPTPN1MEN1POLB | |
| SCHEMBL30307600 | 0.72 | PTPN1 (0.62) | MAOBPTPN1MEN1POLBKMT2A | |
| SCHEMBL18878405 | 0.71 | PTPN1 (0.56) | CYP19A1MAOBPTPN1MEN1POLB | |
| SCHEMBL28600768 | 0.71 | MAPT (0.44) | CYP19A1MAOBPTPN1MEN1POLB | |
| SCHEMBL27924239 | 0.71 | ALOX15 (0.57) | MEN1POLBKMT2AALDH1A1KDM4E | |
| SCHEMBL25824617 | 0.70 | LOXL2 (0.36) | LOXL2MAOBPTPN1PARP1 | |
| SCHEMBL14265470 | 0.70 | CYP1A2 (0.39) | MAOBALDH1A1CES1GPR55LMNA | |
| SCHEMBL29208129 | 0.70 | — | — | |
| SCHEMBL2094794 | 0.70 | ALDH1A1 (0.39) | LOXL2MAOBPOLBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112898259-B | Method for preparing 3-substituted chromanone through nonmetal catalytic hydrogenation | 中国科学院化学研究所 | 2022-05-17 | — | — | CN | disclosed |
| CN-112898259-A | Method for preparing 3-substituted chromanone through nonmetal catalytic hydrogenation | 中国科学院化学研究所 | 2021-06-04 | — | — | CN | disclosed |