Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 6/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31426304 | 0.85 | LOXL2 (0.33) | LOXL2 | |
| SCHEMBL28990308 | 0.83 | MEN1 (0.37) | PTPN1MEN1POLBKMT2APARP1 | |
| SCHEMBL28990332 | 0.79 | TTR (0.41) | MAOBPTPN1MEN1POLBKMT2A | |
| SCHEMBL30307600 | 0.76 | PTPN1 (0.62) | MAOBPTPN1MEN1POLBKMT2A | |
| SCHEMBL27924239 | 0.75 | ALOX15 (0.57) | MEN1POLBKMT2APIK3CAALDH1A1 | |
| SCHEMBL28596607 | 0.75 | LOXL2 (0.37) | LOXL2MAOBPTPN1MEN1POLB | |
| SCHEMBL25824617 | 0.74 | LOXL2 (0.36) | LOXL2MAOBPTPN1PARP1 | |
| SCHEMBL25567716 | 0.73 | MAOB (0.56) | MAOBPTPN1MAOAALDH1A1MAPT | |
| SCHEMBL24696441 | 0.73 | ENPP3 (0.35) | LOXL2ENPP3ENPP1 | |
| SCHEMBL15678569 | 0.72 | LOXL2 (0.50) | LOXL2ENPP3ENPP1KMT2APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991695-B | Method for preparing 3-fluorochromanone by metal-free catalytic hydrogenation | 中国科学院化学研究所 | 2024-06-21 | — | — | CN | disclosed |
| CN-115991695-A | Method for preparing 3-fluorochromanone by metal-free catalytic hydrogenation | 中国科学院化学研究所 | 2023-04-21 | — | — | CN | disclosed |