Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3462461 | 0.81 | MYC (0.67) | MYCLMNACES2CES1KDM4E | |
| SCHEMBL2027018 | 0.81 | MYC (0.60) | MYCLMNAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL3517263 | 0.81 | LMNA (0.49) | MYCLMNACES2CES1KDM4E | |
| SCHEMBL1487887 | 0.80 | LMNA (0.52) | MYCLMNACES2CES1KDM4E | |
| SCHEMBL3516962 | 0.78 | LMNA (0.49) | MYCLMNACES2CES1KDM4E | |
| Methoxymethane SCHEMBL28820448 | 0.76 | LMNA (0.47) | MYCLMNACES2CES1KDM4E | |
| SCHEMBL28887353 | 0.76 | LMNA (0.50) | MYCLMNACES2CES1KDM4E | |
| SCHEMBL461654 | 0.75 | LMNA (0.57) | LMNACES2CES1KDM4EALDH1A1 | |
| SCHEMBL387303 | 0.75 | LMNA (0.57) | MYCLMNACES2CES1KDM4E | |
| SCHEMBL1476486 | 0.74 | CES2 (0.52) | LMNACES2CES1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164494-A | Agents and methods for modulating pathogen activity | 格里菲斯大学 | 2021-07-23 | — | — | CN | disclosed |