SCHEMBL3517263

SCHEMBL3517263

Cc1c(N)cccc1C(=O)C(O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.49
CES2 O00748 2/20 0.49
CES1 P23141 2/20 0.49
ALDH1A1 P00352 4/20 0.45
KDM4E B2RXH2 3/20 0.45
MAPK1 P28482 1/20 0.44
HSD17B10 Q99714 3/20 0.42
NPC1 O15118 1/20 0.42
CASP3 P42574 1/20 0.42
RAB9A P51151 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
HPGD P15428 1/20 0.41
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
PIK3CA P42336 1/20 0.41
FADS1 O60427 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6273723 0.87 LMNA (0.49) LMNACES2CES1ALDH1A1KDM4E
SCHEMBL461654 0.84 LMNA (0.57) LMNACES2CES1ALDH1A1KDM4E
SCHEMBL1487887 0.83 LMNA (0.52) LMNACES2CES1ALDH1A1KDM4E
SCHEMBL1476486 0.83 CES2 (0.52) LMNACES2CES1ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL30785538 0.83 LMNA (0.55) LMNACES2CES1ALDH1A1KDM4E
Acetic Acid SCHEMBL4779745 0.83 LMNA (0.47) LMNACES2CES1ALDH1A1KDM4E
SCHEMBL10394795 0.82 MMP2 (0.58) LMNACES2CES1ALDH1A1KDM4E
SCHEMBL6558242 0.82 LMNA (0.50) LMNACES2CES1ALDH1A1KDM4E
SCHEMBL387303 0.81 LMNA (0.57) LMNACES2CES1ALDH1A1KDM4E
SCHEMBL3516962 0.81 LMNA (0.49) LMNACES2CES1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9992996-B2 Bioactive aniline copolymers AUCKLAND UNISERVICES LTD (NZ) 2018-06-12 US claimed
US-20160235059-A1 BIOACTIVE ANILINE COPOLYMERS AUCKLAND UNISERVICES LIMITED (NZ) 2016-08-18 US claimed
US-7709550-B2 Ink composition, inkjet recording method, printed material, process for producing lithographic printing plate, and lithographic printing plate FUJIFILM CORPORATION (JP) 2010-05-04 US disclosed
EP-1762599-B1 Ink composition, inkjet recording method, printed material, process for producing lithographic plate, and lithographic printing plate FUJIFILM CORP (JP) 2008-03-05 EP disclosed
EP-1762599-A1 Ink composition, inkjet recording method, printed material, process for producing lithographic plate, and lithographic printing plate FUJIFILM Corporation (JP) 2007-03-14 EP disclosed
US-20070052790-A1 Ink composition, inkjet recording method, printed material, process for producing lithographic printing plate, and lithographic printing plate FUJI PHOTO FILM CO., LTD. 2007-03-08 US disclosed
EP-0799247-B1 CHITOSAN SALTS AND PROCESS FOR THE PREPARATION THEREOF KIMBERLY CLARK CO (US) 2002-07-10 EP disclosed
US-5599916-A MIXING A CHITOSAN, WATER AND AN ACID; RECOVERING A WATER-SWELLABLE, WATER-INSOLUBLE CHITOSAN; DISPOSABLE PRODUCTS; DIAPERS; SANITARY NAPKINS KIMBERLY-CLARK CORPORATION (US) 1997-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160235059-A1 BIOACTIVE ANILINE COPOLYMERS ALKBH1, L3MBTL3, AGXT LMNA 1720/4885CES2 720/4885CES1 1177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.