Sugi Predict

Sugi Predict / Compounds / SCHEMBL1476486

SCHEMBL1476486

SCHEMBL1476486

Nc1cccc(C(=O)C(O)c2ccccc2)c1N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CES2 O00748 4/20 0.52
▸ CES1 P23141 4/20 0.52
▸ LMNA P02545 3/20 0.52
▸ MAPK1 P28482 1/20 0.47
▸ ALDH1A1 P00352 3/20 0.44
▸ KDM4E B2RXH2 3/20 0.44
▸ MAPT P10636 2/20 0.42
▸ GAA P10253 1/20 0.42
▸ MMP2 P08253 1/20 0.42
▸ HPGD P15428 1/20 0.40
▸ SRC P12931 1/20 0.39
▸ FADS1 O60427 1/20 0.39
▸ G6PD P11413 1/20 0.38
▸ CASP7 P55210 1/20 0.38
▸ CASP6 P55212 1/20 0.38
▸ CFTR P13569 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ CDC25B P30305 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL4779745 0.95 LMNA (0.47) CES2CES1LMNAMAPK1ALDH1A1
SCHEMBL461654 0.87 LMNA (0.57) CES2CES1LMNAMAPK1ALDH1A1
Hydrochloric Acid SCHEMBL30785538 0.86 LMNA (0.55) CES2CES1LMNAMAPK1ALDH1A1
SCHEMBL10394795 0.85 MMP2 (0.58) CES2CES1LMNAMAPK1ALDH1A1
SCHEMBL3517263 0.83 LMNA (0.49) CES2CES1LMNAMAPK1ALDH1A1
SCHEMBL28154416 0.83 LMNA (0.49) CES2CES1LMNAMAPK1ALDH1A1
SCHEMBL3516962 0.83 LMNA (0.49) CES2CES1LMNAMAPK1ALDH1A1
SCHEMBL28137733 0.83 CES2 (0.49) CES2CES1LMNAMAPK1ALDH1A1
SCHEMBL28956589 0.83 CES2 (0.50) CES2CES1LMNAMAPK1ALDH1A1
SCHEMBL27796168 0.81 LMNA (0.54) CES2CES1LMNAMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107286303-B A kind of aqueous polyurethane acrylate lotion and its aqueous ink used for plastic of preparation 中山大学 2019-05-31 — — CN claimed
CN-107286303-A A kind of aqueous polyurethane acrylate emulsion and its aqueous ink used for plastic of preparation 中山大学 2017-10-24 — — CN claimed
WO-2023105480-A1 POLYETHERIMIDE HAVING REACTIVE BRANCHING SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-06-15 — — WO disclosed
US-20210280861-A1 NEGATIVE ELECTRODE AND METHOD FOR PRODUCING NEGATIVE ELECTRODE, AND ELECTRODE BINDING AGENT KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2021-09-09 — — US disclosed
CN-109537299-A A kind of waterborne polyurethane coating agent and preparation method thereof 广西南宁桂尔创环保科技有限公司 2019-03-29 — — CN disclosed
CN-109504269-A A kind of polyurethane building coating and preparation method thereof 广西南宁桂尔创环保科技有限公司 2019-03-22 — — CN disclosed
CN-105873665-B Composite polyamide membrane post-treated with nitrous acid 陶氏环球技术有限责任公司 2019-01-01 — — CN disclosed
CN-107540806-A Polyurethane type high molecular ultraviolet absorbent 台湾永光化学工业股份有限公司 2018-01-05 — — CN disclosed
US-9688606-B2 Process for acidic scrubbing of dinitrotoluene in the presence of hydrocyanic acid BASF SE (DE) 2017-06-27 — — US disclosed
CN-104893539-B Preparation method of hydrophobic and flame-retardant PU (polyurethane) coating 西安科技大学 2017-04-19 — — CN disclosed
US-20160251302-A1 PROCESS FOR ACIDIC SCRUBBING OF DINITROTOLUENE IN THE PRESENCE OF HYDROCYANIC ACID BASF SE (DE) 2016-09-01 — — US disclosed
CN-1326963-C Release coating containing thermoplastic silicone-containing polymer 3M INNOVATIVE PROPERTIES CO (US) 2007-07-18 — — CN disclosed
US-20060246450-A1 Ligational encoding of small molecules NUEVOLUTION A/S (DK) 2006-11-02 — — US disclosed
WO-2006004791-A1 ARYL-SUBSTITUTED BENZIMIDAZOLE AND IMIDAZOPYRIDINE ETHERS AS ANTI-CANCER AGENTS JANSSEN PHARMACEUTICA, N.V. (BE) 2006-01-12 — — WO disclosed
CN-1653148-A Release coating containing thermoplastic silicone-containing polymer 3M INNOVATIVE PROPERTIES CO (US) 2005-08-10 — — CN disclosed
US-6855713-B2 Benzimidazole derivatives, a process for their manufacture and use as a medicine BOEHRINGER INGELHEIM PHARMA KG (DE) 2005-02-15 — — US disclosed
CN-1495218-A Anti-bacterial high molecule and its preparation method, anti-bacterial high-molecule covering film and its preparation method and product with said surface covering film ���׿ƹɷ����޹�˾ 2004-05-12 — — CN disclosed
US-20030130265-A1 Benzimidazole derivatives, a process for their manufacture and use as a medicine BOEHRINGER INGELHEIM PHARMA KG (DE) 2003-07-10 — — US disclosed
US-6316623-B1 USEFUL FOR SCREENING IN BIOLOGICAL ASSAYS IN ORDER TO IDENTIFY PHARMACEUTICALLY USEFUL COMPOUNDS ISIS PHARMACEUTICALS, INC. 2001-11-13 — — US disclosed
US-5281690-A Multilayer element with polymer layers BREWER SCIENCE, INC. (US) 1994-01-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060246450-A1 Ligational encoding of small molecules POLI, PCNA, LIG4 CES2 3865/4885CES1 4587/4885LMNA 2075/4885
US-20030130265-A1 Benzimidazole derivatives, a process for their manufacture and use as a medicine TPSAB1, PRSS3, TPSD1 CES2 710/4885CES1 41/4885LMNA 1896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.