Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1238436 | 0.77 | ALDH1A1 (0.40) | AKR1C3CYP3A4CYP2C9FBP1ALDH1A1 | |
| SCHEMBL2221643 | 0.75 | ALDH1A1 (0.39) | AKR1C3CYP3A4CYP2C9FBP1ALDH1A1 | |
| SCHEMBL2362850 | 0.74 | ALDH1A1 (0.39) | AKR1C3CYP3A4CYP2C9FBP1ALDH1A1 | |
| 1,3-Propanediol SCHEMBL2865031 | 0.71 | FBP1 (0.36) | AKR1C3CYP3A4CYP2C9FBP1ALDH1A1 | |
| SCHEMBL2361798 | 0.69 | GAA (0.41) | AKR1C3CYP3A4CYP2C9ALDH1A1TSHR | |
| SCHEMBL7031297 | 0.66 | ALDH1A1 (0.41) | AKR1C3CYP3A4CYP2C9FBP1ALDH1A1 | |
| SCHEMBL12593472 | 0.66 | ALDH1A1 (0.46) | AKR1C3FBP1ALDH1A1TSHRRECQL | |
| SCHEMBL14765003 | 0.66 | ALDH1A1 (0.46) | AKR1C3FBP1ALDH1A1TSHRRECQL | |
| SCHEMBL9709645 | 0.64 | FBP1 (0.45) | AKR1C3CYP3A4CYP2C9FBP1ALDH1A1 | |
| SCHEMBL4631524 | 0.64 | FBP1 (0.45) | AKR1C3CYP3A4CYP2C9FBP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318795-B2 | Antioxidant polymers containing [1,2]-dithiolane moieties and uses thereof | CEDARS-SINAI MEDICAL CENTER (US) | 2012-11-27 | — | — | US | disclosed |
| US-20100098653-A1 | ANTIOXIDANT POLYMERS CONTAINING [1,2]-DITHIOLANE MOIETIES AND USES THEREOF | CEDARS-SINAI MEDICAL CENTER (US) | 2010-04-22 | — | — | US | disclosed |
| EP-2125775-A1 | ANTIOXIDANT POLYMERS CONTAINING [1,2]-DITHIOLANE MOIETIES AND USES THEREOF | Cedars-Sinai Medical Center (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008106640-A1 | ANTIOXIDANT POLYMERS CONTAINING [1,2]-DITHIOLANE MOIETIES AND USES THEREOF | CEDARS-SINAI MEDICAL CENTER (US) | 2008-09-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100098653-A1 | ANTIOXIDANT POLYMERS CONTAINING [1,2]-DITHIOLANE MOIETIES AND USES THEREOF | GPX1, GPX4, LPO | AKR1C3 939/4885CYP3A4 2888/4885CYP2C9 2220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.