Acrylamide

Acrylamide

SCHEMBL28599343

C=CC(=O)NC[N+](C)(C)CCC.C=CC(N)=O.CC(C)CS(=O)(=O)O.[Cl-]

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Acrylamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL28592507 0.97 ZDHHC20 (0.33) ZDHHC20ZDHHC2
Acrylamide SCHEMBL28870529 0.86 ZDHHC20 (0.41) ZDHHC20ZDHHC2
Hydrochloric Acid SCHEMBL336794 0.80 ZDHHC20 (0.46) ZDHHC20ZDHHC2
SCHEMBL4126549 0.79 ZDHHC20 (0.47) ZDHHC20ZDHHC2
Acrylic Acid SCHEMBL28917584 0.79
Bromide SCHEMBL25324391 0.77 ZDHHC20 (0.46) ZDHHC20ZDHHC2
Acrylamide SCHEMBL27695548 0.77 TSHR (0.41)
Chloromethane SCHEMBL28028247 0.76 ZDHHC20 (0.44) ZDHHC20ZDHHC2
Acrylamide SCHEMBL195051 0.76 TSHR (0.46)
Acrylamide SCHEMBL6835393 0.76 TSHR (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109425686-B Method for detecting cationic degree of synthetic polymer for drilling fluid 中石化石油工程技术服务有限公司 2021-07-23 CN disclosed