Chloromethane

Chloromethane

SCHEMBL28028247

C=CC(=O)NC[N+](C)(C)CCC.CCl

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.44
ZDHHC2 Q9UIJ5 1/20 0.44
TSHR P16473 3/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
TGM2 P21980 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4126549 0.96 ZDHHC20 (0.47) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
Bromide SCHEMBL25324391 0.95 ZDHHC20 (0.46) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
Hydrochloric Acid SCHEMBL336794 0.95 ZDHHC20 (0.46) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
Acrylic Acid SCHEMBL396773 0.88 ZDHHC20 (0.41) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
Acrylamide SCHEMBL28870529 0.88 ZDHHC20 (0.41) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL29142619 0.86 ZDHHC20 (0.53) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL28180741 0.83 ZDHHC20 (0.37) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
Hydrochloric Acid SCHEMBL28470855 0.81 ZDHHC20 (0.57) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL9451758 0.81 TSHR (0.48) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
Hydrochloric Acid SCHEMBL4534755 0.79 TSHR (0.46) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107849821-A Aldehyde-functionalized polymers for paper strength and dewatering 艺康美国股份有限公司 2018-03-27 CN disclosed
CN-104768527-A External preparation for skin FUJIFILM CORP 2015-07-08 CN disclosed