Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2368735 | 0.85 | GRIN2C (0.56) | PRKCZALDH1A1HPGDMEN1LMNA | |
| SCHEMBL12466271 | 0.83 | ADORA1 (0.49) | PRKCZALDH1A1HPGDMEN1LMNA | |
| SCHEMBL9720150 | 0.83 | ALDH1A1 (0.53) | PRKCZALDH1A1HPGDMEN1LMNA | |
| SCHEMBL2367950 | 0.83 | PRKCZ (0.63) | PRKCZALDH1A1HPGDMEN1LMNA | |
| SCHEMBL13838083 | 0.82 | PRKCZ (0.61) | PRKCZALDH1A1HPGDMEN1LMNA | |
| SCHEMBL8188234 | 0.81 | KMT2A (0.65) | PRKCZALDH1A1HPGDMEN1LMNA | |
| SCHEMBL8196570 | 0.81 | ALDH1A1 (0.62) | PRKCZALDH1A1HPGDMEN1LMNA | |
| SCHEMBL1799330 | 0.80 | KMT2A (0.69) | PRKCZALDH1A1HPGDMEN1LMNA | |
| SCHEMBL6926065 | 0.80 | MPL (0.50) | PRKCZALDH1A1HPGDANO1HSD17B10 | |
| SCHEMBL8290362 | 0.80 | PRKCZ (0.75) | PRKCZALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108938625-B | Application of 2-arylformamido thiophene-3-carboxylic acid derivative as ANO1 protein inhibitor and preparation method thereof | 北京大学 | 2021-06-29 | — | — | CN | disclosed |