Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.51 |
| ▸ | HPGDS | O60760 | 2/20 | 0.50 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CTSA | P10619 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16496342 | 0.83 | BAZ2B (0.65) | BAZ2BROCK2ROCK1HPGDSMAPK1 | |
| SCHEMBL28601974 | 0.83 | MEN1 (0.61) | ROCK2ROCK1HPGDSMAPK3MAPK1 | |
| SCHEMBL16495348 | 0.79 | CTSA (0.56) | BAZ2BMEN1KMT2ACTSA | |
| SCHEMBL28598671 | 0.79 | CTSA (0.59) | ROCK2ROCK1MAPK3MAPK1CYP1A2 | |
| SCHEMBL28603586 | 0.77 | KMO (0.51) | ROCK2ROCK1MAPK3MAPK1CTSA | |
| SCHEMBL16496169 | 0.76 | BAZ2B (0.62) | BAZ2BROCK2HPGDSLDHAPRKG1 | |
| SCHEMBL16496172 | 0.76 | BAZ2B (0.62) | BAZ2BROCK2HPGDSLDHAPRKG1 | |
| SCHEMBL16495423 | 0.76 | NPC1 (0.69) | BAZ2BROCK2ROCK1HPGDSMAPK1 | |
| SCHEMBL16495693 | 0.75 | ROCK2 (0.60) | BAZ2BROCK2ROCK1HPGDSMAPK1 | |
| SCHEMBL28611023 | 0.75 | TUBB4A (0.50) | ROCK2ROCK1MAPK3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407824-B | Aryl formamide compound and preparation method, pharmaceutical composition and application thereof | 安徽医科大学 | 2021-07-02 | — | — | CN | disclosed |