Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 9/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 9/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 9/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 9/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19878642 | 0.86 | GABRA1 (0.41) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL12867867 | 0.83 | ALOX15 (0.48) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL30454328 | 0.78 | GABRA1 (0.38) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL5838109 | 0.77 | ALDH1A1 (0.39) | KDM4EELANEALDH1A1HSD17B10 | |
| SCHEMBL645520 | 0.77 | RAB9A (0.56) | GAANPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL7165649 | 0.76 | HCAR2 (0.52) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL30302109 | 0.76 | RAB9A (0.55) | GAANPC1RAB9ASMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL28853901 | 0.76 | RAB9A (0.55) | GAANPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL70624 | 0.75 | GAA (0.67) | KDM4EGLAGAACA12CA1 | |
| SCHEMBL109451 | 0.75 | CA1 (0.61) | GABRA1GABRG2GABRB3GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164571-A | Inhibition of ubiquitin-specific peptidase 9X | 福马治疗股份有限公司 | 2021-07-23 | — | — | CN | disclosed |