Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 5/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | TNKS | O95271 | 2/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7823681 | 0.85 | KDM4E (0.51) | KDM4ENR4A2ALDH1A1LMNAMAPT | |
| SCHEMBL1721017 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1LMNAMAPTGAA | |
| SCHEMBL5705595 | 0.79 | NR4A2 (0.67) | KDM4ESMN1; SMN2NR4A2PKMALDH1A1 | |
| SCHEMBL17952494 | 0.78 | ALDH1A1 (0.62) | KDM4ESMN1; SMN2NR4A2ALDH1A1LMNA | |
| SCHEMBL29031850 | 0.77 | NR4A2 (0.48) | KDM4ENR4A2ALDH1A1LMNAMAPT | |
| SCHEMBL30472331 | 0.77 | NR4A2 (0.48) | KDM4ENR4A2ALDH1A1LMNAMAPT | |
| SCHEMBL4512438 | 0.75 | RAB9A (0.61) | KDM4ESMN1; SMN2NR4A2PKMALDH1A1 | |
| SCHEMBL28601535 | 0.75 | KDM4E (0.44) | KDM4EALDH1A1LMNAGAAHPGD | |
| SCHEMBL31146421 | 0.75 | THRB (0.52) | KDM4ESMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL181822 | 0.75 | THRB (0.52) | KDM4ESMN1; SMN2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947900-B | Method for synthesizing heterocyclic compound by photoinduced metal-free catalyzed carbon arylation cascade reaction | 河南大学 | 2021-07-30 | — | — | CN | disclosed |