SCHEMBL28601535

SCHEMBL28601535

CC(=O)c1c(C2CC2)[nH]c(=O)c2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.44
ALDH1A1 P00352 6/20 0.38
GAA P10253 2/20 0.38
HPGD P15428 1/20 0.38
TUBB4A P04350 2/20 0.38
TUBB P07437 2/20 0.38
TUBA3C P0DPH7 2/20 0.38
TUBA1B P68363 2/20 0.38
TUBA4A P68366 2/20 0.38
TUBB4B P68371 2/20 0.38
TUBB3 Q13509 2/20 0.38
TUBB2A Q13885 2/20 0.38
TUBB8 Q3ZCM7 2/20 0.38
TUBA3E Q6PEY2 2/20 0.38
TUBA1A Q71U36 2/20 0.38
TUBA1C Q9BQE3 2/20 0.38
TUBB6 Q9BUF5 2/20 0.38
TUBB2B Q9BVA1 2/20 0.38
TUBB1 Q9H4B7 2/20 0.38
HTT P42858 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28601441 0.75 KDM4E (0.50) KDM4EALDH1A1GAAHPGDHTT
SCHEMBL1721017 0.73 KDM4E (0.49) KDM4EALDH1A1GAAHPGDHTT
SCHEMBL29722719 0.70 SMN1; SMN2 (0.48) KDM4EALDH1A1NPSR1HSD17B10LMNA
SCHEMBL181822 0.69 THRB (0.52) KDM4EALDH1A1GAAHPGDHTT
SCHEMBL31146421 0.69 THRB (0.52) KDM4EALDH1A1GAAHPGDHTT
SCHEMBL6646606 0.67 HTR2A (0.48) KDM4EPARP1TNKSTNKS2
SCHEMBL1666371 0.67 THRB (0.50) KDM4EALDH1A1GAAHPGDHTT
SCHEMBL4984795 0.66 TUBB4A (0.49) KDM4ETUBB4ATUBBTUBA3CTUBA1B
SCHEMBL5251920 0.65 TUBB4A (0.54) KDM4EALDH1A1HPGDTUBB4ATUBB
SCHEMBL7823681 0.65 KDM4E (0.51) KDM4EALDH1A1GAAHPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108947900-B Method for synthesizing heterocyclic compound by photoinduced metal-free catalyzed carbon arylation cascade reaction 河南大学 2021-07-30 CN disclosed