Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 2/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17870956 | 0.85 | ALDH1A1 (0.42) | CA12CA2CA9TSHRMAPT | |
| SCHEMBL5698977 | 0.84 | RAB9A (0.41) | CA12CA2CA9ALOX15TSHR | |
| Sulfuric Acid SCHEMBL127139 | 0.82 | KDM4E (0.50) | LMNAKDM4EMAPK1 | |
| SCHEMBL28507225 | 0.80 | KDM4E (0.48) | LMNAKDM4E | |
| SCHEMBL21954 | 0.79 | KDM4E (0.56) | ALOX15ALDH1A1HTTLMNAKDM4E | |
| SCHEMBL28780748 | 0.78 | CA12 (0.58) | CA12CA2CA9ALOX15TSHR | |
| Ammonia Solution, Strong SCHEMBL23532663 | 0.78 | KDM4E (0.54) | ALOX15ALDH1A1HTTLMNAKDM4E | |
| Hydrochloric Acid SCHEMBL111099 | 0.78 | KDM4E (0.54) | ALOX15ALDH1A1HTTLMNAKDM4E | |
| SCHEMBL111005 | 0.78 | KDM4E (0.50) | TSHRALDH1A1LMNAKDM4EMAPK1 | |
| Acetone SCHEMBL28357455 | 0.78 | KDM4E (0.54) | ALOX15ALDH1A1HTTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015013780-A1 | COMPOSITION COMPRISING AN AMINOSILICONE, A CATIONIC SURFACTANT AND A CATIONIC ASSOCIATIVE POLYMER | L' OREAL (FR) | 2015-02-05 | — | — | WO | disclosed |
| EP-1707182-B2 | Dye composition comprising a fatty acid ester and process for dyeing keratin fibres using the same | ORÉAL L (FR) | 2014-09-10 | — | — | EP | disclosed |
| EP-1707182-B1 | Dye composition comprising a fatty acid ester and process for dyeing keratin fibres using the same | OREAL (FR) | 2010-10-20 | — | — | EP | disclosed |
| EP-1652554-B1 | Composition comprising at least one carboycanine, process of treating keratinic fibres, kit and use of said composition | OREAL (FR) | 2010-01-13 | — | — | EP | disclosed |
| EP-1652553-B1 | Composition comprising at least one carbocyanine, process of treating keratinic fibres, kit and use of said composition | OREAL (FR) | 2009-06-03 | — | — | EP | disclosed |
| EP-1458338-B1 | DYEING COMPOSITION FOR KERATINOUS FIBERS COMPRISING AN OXYETHYLENE RAPESEED FATTY ACID AMIDE | OREAL (FR) | 2006-09-20 | — | — | EP | disclosed |
| EP-1652553-A1 | Composition comprising at least one carbocyanine, process of treating keratinic fibres, kit and use of said composition | L'OREAL (FR) | 2006-05-03 | — | — | EP | disclosed |
| EP-1652554-A1 | Composition comprising at least one carboycanine, process of treating keratinic fibres, kit and use of said composition | L'OREAL (FR) | 2006-05-03 | — | — | EP | disclosed |
| EP-1357887-B1 | COSMETIC COMPOSITION COMPRISING A FIXING POLYMER AND A CATIONIC POLY(VINYLLACTAM) | OREAL (FR) | 2006-03-29 | — | — | EP | disclosed |
| EP-1634575-A1 | Composition comprising at least one carbocyanine, process of treating keratinic fibres, kit and use of said composition | L'OREAL (FR) | 2006-03-15 | — | — | EP | disclosed |
| US-20050125912-A1 | Dyeing composition for keratinous fibers comprising an oxyethylene rapeseed fatty acid amide | L'OREAL S.A. (FR) | 2005-06-16 | — | — | US | disclosed |
| EP-1458338-A2 | DYEING COMPOSITION FOR KERATINOUS FIBERS COMPRISING AN OXYETHYLENE RAPESEED FATTY ACID AMIDE | L'OREAL (FR) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003053329-A2 | DYEING COMPOSITION FOR KERATINOUS FIBERS COMPRISING AN OXYETHYLENE RAPESEED FATTY ACID AMIDE | L'OREAL (FR) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050125912-A1 | Dyeing composition for keratinous fibers comprising an oxyethylene rapeseed fatty acid amide | KRT18, ELOVL5, FADS1 | CA12 1055/4885CA2 2244/4885CA9 949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.