Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83920 | 0.88 | RAD52 (0.44) | RAB9ANPC1RAD52ALDH1A1MAPT | |
| SCHEMBL4779656 | 0.86 | DNM1 (0.32) | RAB9ANPC1L3MBTL1RAD52ALDH1A1 | |
| SCHEMBL17202969 | 0.85 | DNM1 (0.31) | RAB9ANPC1L3MBTL1RAD52ALDH1A1 | |
| SCHEMBL2860170 | 0.84 | CA12 (0.52) | RAB9ACA12CA2CA9RAD52 | |
| SCHEMBL29710199 | 0.79 | CYP2C19 (0.45) | L3MBTL1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28347130 | 0.78 | RAD52 (0.37) | RAD52ALDH1A1MAPTTSHRKDM4E | |
| SCHEMBL18036284 | 0.77 | CA12 (0.38) | L3MBTL1CA12CA2CA9RAD52 | |
| SCHEMBL87329 | 0.75 | RAD52 (0.41) | RAD52ALDH1A1MAPTTSHRMEN1 | |
| SCHEMBL9128677 | 0.75 | RAB9A (0.37) | RAB9ANPC1RAD52ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL444004 | 0.74 | RAB9A (0.35) | RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1676603-A1 | Use of an association of an associative polymer and an amphiphilic dibloc copolymer for thickening of cosmetic compositions | L'OREAL (FR) | 2006-07-05 | — | — | EP | disclosed |
| EP-1502582-A1 | Sunscreen emulsions containing gemini surfactants and associative polymers | L'OREAL (FR) | 2005-02-02 | — | — | EP | disclosed |