SCHEMBL1798900

SCHEMBL1798900

O=C1CCCc2cc(Cl)ccc21

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 9/20 0.67
MAOB P27338 9/20 0.67
PRKCI P41743 1/20 0.67
HSD17B1 P14061 2/20 0.54
CYP2A6 P11509 1/20 0.53
GRM5 P41594 1/20 0.51
BAZ2B Q9UIF8 1/20 0.50
SRD5A1 P18405 2/20 0.47
SRD5A2 P31213 1/20 0.47
MEN1 O00255 1/20 0.47
MAPK1 P28482 1/20 0.47
KMT2A Q03164 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
METAP1 P53582 1/20 0.46
HTT P42858 1/20 0.46
CASP1 P29466 1/20 0.46
CASP7 P55210 1/20 0.46
HSD17B10 Q99714 1/20 0.46
VHL P40337 1/20 0.44
ELOC Q15369 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5108894 0.96 MAOA (0.61) MAOAMAOBPRKCIHSD17B1CYP2A6
SCHEMBL17011806 0.91 MAOA (0.56) MAOAMAOBPRKCIHSD17B1CYP2A6
SCHEMBL28603 0.88 CASP1 (0.59) MAOAMAOBPRKCIHSD17B1GRM5
SCHEMBL31029247 0.88 CASP1 (0.59) MAOAMAOBPRKCIHSD17B1GRM5
SCHEMBL4418225 0.85 HSD17B1 (0.71) MAOAMAOBPRKCIHSD17B1CYP2A6
Hydrochloric Acid SCHEMBL28688881 0.84 CASP1 (0.55) MAOAMAOBPRKCIHSD17B1GRM5
SCHEMBL1998628 0.84 MAOA (0.59) MAOAMAOBPRKCIHSD17B1CYP2A6
SCHEMBL29673182 0.84 MAOA (0.59) MAOAMAOBPRKCIHSD17B1CYP2A6
Aluminum Chloride Anhydrous SCHEMBL28688879 0.82 CASP1 (0.53) MAOAMAOBPRKCIHSD17B1GRM5
SCHEMBL10190637 0.81 GRM5 (0.75) MAOAMAOBPRKCIHSD17B1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 340 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115108928-B Nitrogen mustard-tetralone derivative, preparation method and application thereof 广东海洋大学 2024-06-11 CN claimed
CN-108299169-B Synthesis method of 6-chloro-3, 4-dihydro-2H-1-naphthalenone 南京杰运医药科技有限公司 2021-04-30 CN claimed
CN-109803975-B Binuclear metal complex and electronic device, especially organic electroluminescent device, containing the same UDC爱尔兰有限公司 2026-05-22 CN disclosed
US-20260035362-A1 GLP-1R AGONISTS AND USES THEREOF QILU REGOR THERAPEUTICS INC (CN) 2026-02-05 US disclosed
EP-4678644-A1 SUBSTITUTED DIHYDROTHIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF Shanghai Yidi Biotechnology Co., Ltd. (CN) 2026-01-14 EP disclosed
US-20250289812-A1 COMPOUND FOR TREATING THROMBOTIC DISEASES RUIJIN HOSPITAL, SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE (CN) 2025-09-18 US disclosed
EP-4596544-A1 EP300/CBP REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF Miracure Biotechnology Limited (CN) 2025-08-06 EP disclosed
US-12365670-B2 GLP-IR agonists and uses thereof QILU REGOR THERAPEUTICS INC. (CN) 2025-07-22 US disclosed
EP-4573086-A1 METHANOGEN INHIBITORS Agrizeronz Limited Partnership (NZ) 2025-06-25 EP disclosed
CN-120152713-A Tricyclic aryl derivatives and compositions and methods thereof 昂胜医疗科技公司 2025-06-13 CN disclosed
CN-115335374-B GLP-1R modulating compounds 吉利德科学公司 2025-05-27 CN disclosed
US-4051233-A ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIPRURITIC SYNTEX CORPORATION (US) 1977-09-27 US disclosed
US-4051248-A CENTRAL NERVOUS SYSTEM DEPRESSANTS, NEUROLEPTIC AGENTS E. R. SQUIBB & SONS, INC. (US) 1977-09-27 US disclosed
US-4048330-A Compositions containing 2-(6'-substituted-2'-naphthyl)acetic acid esters used for treating inflammation, pain or pyrexia SYNTEX CORPORATION (US) 1977-09-13 US disclosed
US-4009197-A 2-(6-Substituted-2'-naphthyl) acetic acid derivatives and the salts and esters thereof SYNTEX CORPORATION (PM) 1977-02-22 US disclosed
US-4001301-A ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, ANTI-PRURITIC SYNTEX CORPORATION (PM) 1977-01-04 US disclosed
US-3998966-A Anti-inflammatory, analgesic, anti-pyretic and anti-pruritic 6-substituted 2-naphthyl acetic acid derivative-containing compositions and methods of use thereof SYNTEX CORPORATION (PM) 1976-12-21 US disclosed
US-3980699-A ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETIC, ANTIPRURITIC SYNTEX CORPORATION (PM) 1976-09-14 US disclosed
US-3978124-A ANALGESIC, ANTIPYRETIC SYNTEX CORPORATION (PM) 1976-08-31 US disclosed
US-3940418-A Esters and amides of 4,5-dihydrobenz[g]indazole-3-carboxylic acids and related compounds G. D. SEARLE & CO. (US) 1976-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035362-A1 GLP-1R AGONISTS AND USES THEREOF GLP1R, GPR119, IAPP MAOA 4566/4885MAOB 4431/4885PRKCI 689/4885
US-20250289812-A1 COMPOUND FOR TREATING THROMBOTIC DISEASES ITGB3, SRC, FYN MAOA 4348/4885MAOB 3738/4885PRKCI 372/4885
US-12365670-B2 GLP-IR agonists and uses thereof GLP1R, GPR119, GIPR MAOA 3447/4885MAOB 3041/4885PRKCI 1396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.