Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 2/20 | 0.41 |
| ▸ | RET | P07949 | 2/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.41 |
| ▸ | BLK | P51451 | 2/20 | 0.41 |
| ▸ | STK3 | Q13188 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.41 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.41 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28919461 | 0.90 | MAOA (0.42) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL28603992 | 0.89 | KDR (0.39) | KDRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL28601605 | 0.89 | KDR (0.39) | KDRMEN1KMT2ANPC1RAB9A | |
| Aza-Flavanone SCHEMBL28606333 | 0.88 | MAOA (0.45) | MAPTSMN1; SMN2ALDH1A1CCKBR | |
| SCHEMBL28614837 | 0.85 | KDR (0.40) | KDRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL28603909 | 0.85 | KDR (0.40) | KDRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL28919462 | 0.85 | FPR1 (0.48) | MEN1KMT2ARAB9ATP53POLB | |
| SCHEMBL28601602 | 0.85 | FPR1 (0.48) | MEN1KMT2ARAB9ATP53POLB | |
| SCHEMBL28606031 | 0.85 | MAPT (0.40) | GAAMEN1KMT2ACYP3A4NPC1 | |
| SCHEMBL28608104 | 0.84 | POLB (0.39) | GAAMEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558756-B | 2-aryl-2, 3-dihydro-4 (1H) -quinolinone semicarbazone compound and application thereof | 沈阳药科大学 | 2021-08-03 | — | — | CN | claimed |
| CN-108558756-B | 2-aryl-2, 3-dihydro-4 (1H) -quinolinone semicarbazone compound and application thereof | 沈阳药科大学 | 2021-08-03 | — | — | CN | disclosed |