SCHEMBL28604397

SCHEMBL28604397

CCCC(N)S(=O)(=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.50
PSIP1 O75475 1/20 0.47
MMP1 P03956 4/20 0.44
MMP13 P45452 4/20 0.44
MMP7 P09237 3/20 0.44
MMP12 P39900 3/20 0.44
ACE P12821 2/20 0.44
TDP1 Q9NUW8 1/20 0.41
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA12 O43570 1/20 0.40
CA3 P07451 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40
PLA2G7 Q13093 1/20 0.40
CA9 Q16790 1/20 0.40
CA13 Q8N1Q1 1/20 0.40
CA14 Q9ULX7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19292951 0.87 MMP13 (0.48) SMN1; SMN2PSIP1MMP1MMP13MMP7
SCHEMBL28895074 0.84 PSIP1 (0.50) SMN1; SMN2PSIP1MMP1MMP13MMP7
SCHEMBL27661879 0.83 GAA (0.50) MMP1MMP13TDP1CA1CA2
SCHEMBL28962151 0.83 CA12 (0.51) SMN1; SMN2MMP1MMP13CA1CA2
SCHEMBL12370397 0.82 SMN1; SMN2 (0.56) SMN1; SMN2PSIP1MMP1MMP13MMP7
SCHEMBL28820920 0.80 MMP1 (0.54) SMN1; SMN2PSIP1MMP1MMP13MMP7
SCHEMBL27284049 0.79 ALDH1A1 (0.50) CA1CA2CA12CA4CA9
Bromide SCHEMBL7514743 0.78 ALDH1A1 (0.49) CA1CA2CA12CA4CA9
SCHEMBL27560669 0.78 MMP13 (0.44) MMP1MMP13MMP7MMP12ACE
SCHEMBL8732760 0.78 CA12 (0.44) SMN1; SMN2PSIP1TDP1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-213687351-U N-butylbenzene sulfonamide synthesis is with quick cooling arrangement 南通沃兰化工有限公司 2021-07-13 CN disclosed