Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 3/20 | 0.45 |
| ▸ | MMP7 | P09237 | 3/20 | 0.45 |
| ▸ | MMP12 | P39900 | 3/20 | 0.45 |
| ▸ | MMP13 | P45452 | 3/20 | 0.45 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2445638 | 0.89 | MMP13 (0.54) | SMN1; SMN2PSIP1MMP1MMP7MMP12 | |
| SCHEMBL21498156 | 0.85 | MMP13 (0.48) | SMN1; SMN2PSIP1MMP1MMP7MMP12 | |
| SCHEMBL2446838 | 0.83 | PSIP1 (0.52) | SMN1; SMN2PSIP1MMP1MMP7MMP12 | |
| SCHEMBL28121988 | 0.82 | PRKDC (0.46) | SMN1; SMN2PSIP1MMP1MMP7MMP12 | |
| SCHEMBL15948905 | 0.82 | CA2 (0.57) | SMN1; SMN2MMP1MMP13ALDH1A1CYP2C9 | |
| SCHEMBL23106681 | 0.82 | CA2 (0.57) | SMN1; SMN2MMP1MMP13ALDH1A1CYP2C9 | |
| SCHEMBL28023639 | 0.82 | SMN1; SMN2 (0.42) | SMN1; SMN2PSIP1MMP1MMP7MMP12 | |
| SCHEMBL28604397 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2PSIP1MMP1MMP7MMP12 | |
| SCHEMBL28820920 | 0.82 | MMP1 (0.54) | SMN1; SMN2PSIP1MMP1MMP7MMP12 | |
| SCHEMBL14537429 | 0.81 | MMP2 (0.44) | SMN1; SMN2MMP1MMP7MMP13ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103509135-B | Olefin polymerization catalyst component, preparation method and application thereof | CHINA PETROLEUM & CHEMICAL | 2015-07-22 | — | — | CN | disclosed |
| US-7993879-B2 | Fluorescent protein sensors for detection of analytes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-08-09 | — | — | US | disclosed |